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Clinical and sociodemographic features and quality of life in patients with atopic dermatitis who attended dermatology teaching clinics in Medellín, Antioquia and its metropolitan area.在麦德林、安蒂奥基亚及其大都市区的皮肤科教学诊所就诊的特应性皮炎患者的临床和社会人口学特征及生活质量。
Biomedica. 2021 Dec 15;41(4):676-691. doi: 10.7705/biomedica.5978.
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Higher self-reported severity of atopic dermatitis in adults is associated with poorer self-reported health-related quality of life in France, Germany, the U.K. and the U.S.A.在法国、德国、英国和美国,成年人自我报告的特应性皮炎严重程度越高,其自我报告的与健康相关的生活质量就越差。
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Atopic dermatitis is associated with a decrement in health-related quality of life.特应性皮炎与健康相关生活质量的下降有关。
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Association of Inadequately Controlled Disease and Disease Severity With Patient-Reported Disease Burden in Adults With Atopic Dermatitis.特应性皮炎成人患者疾病控制不佳和疾病严重程度与患者报告疾病负担的相关性。
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General and Skin-Specific Health-Related Quality of Life in Patients With Atopic Dermatitis Before and During the COVID-19 Pandemic.特应性皮炎患者在 COVID-19 大流行前后的总体和皮肤特异性健康相关生活质量。
Dermatitis. 2022;33(6S):S92-S103. doi: 10.1097/DER.0000000000000908. Epub 2022 Jun 8.

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An Bras Dermatol. 2025 May-Jun;100(3):470-486. doi: 10.1016/j.abd.2024.05.011. Epub 2025 Mar 20.
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Healthcare Disparities in Atopic Dermatitis in Latin America: A Narrative Review.拉丁美洲特应性皮炎的医疗保健差异:一项叙述性综述。
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本文引用的文献

1
How does parental history of atopic disease predict the risk of atopic dermatitis in a child? A systematic review and meta-analysis.父母有特应性疾病史如何预测儿童特应性皮炎的风险?系统评价和荟萃分析。
J Allergy Clin Immunol. 2020 Apr;145(4):1182-1193. doi: 10.1016/j.jaci.2019.12.899. Epub 2019 Dec 28.
2
Comorbidities and the impact of atopic dermatitis.共病和特应性皮炎的影响。
Ann Allergy Asthma Immunol. 2019 Aug;123(2):144-151. doi: 10.1016/j.anai.2019.04.020. Epub 2019 Apr 26.
3
Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section IV: Treatment Options for the Management of Atopic Dermatitis.成人特应性皮炎评估与管理方法:一份共识文件。第四章:特应性皮炎管理的治疗选择。
J Cutan Med Surg. 2018 Nov/Dec;22(1_suppl):21S-29S. doi: 10.1177/1203475418805721.
4
Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section I: Pathophysiology of Atopic Dermatitis and Implications for Systemic Therapy.成人特应性皮炎评估与管理方法:一份共识文件。第一部分:特应性皮炎的病理生理学及其对全身治疗的意义。
J Cutan Med Surg. 2018 Nov/Dec;22(1_suppl):6S-9S. doi: 10.1177/1203475418803626.
5
Major Comorbidities of Atopic Dermatitis: Beyond Allergic Disorders.特应性皮炎的主要合并症:超越过敏障碍。
Am J Clin Dermatol. 2018 Dec;19(6):821-838. doi: 10.1007/s40257-018-0383-4.
6
Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I.基于共识的欧洲成人和儿童特应性皮炎(特应性湿疹)治疗指南:第一部分。
J Eur Acad Dermatol Venereol. 2018 May;32(5):657-682. doi: 10.1111/jdv.14891.
7
Dupilumab: A review of its use in the treatment of atopic dermatitis.度普利尤单抗:治疗特应性皮炎的研究进展。
J Am Acad Dermatol. 2018 Mar;78(3 Suppl 1):S28-S36. doi: 10.1016/j.jaad.2017.12.022.
8
[Epidemiology of atopic dermatitis].[特应性皮炎的流行病学]
Ann Dermatol Venereol. 2017 Dec;144 Suppl 5:VS4-VS7. doi: 10.1016/S0151-9638(18)30085-1.
9
Atopic dermatitis yardstick: Practical recommendations for an evolving therapeutic landscape.特应性皮炎评估工具:不断发展的治疗领域的实用建议。
Ann Allergy Asthma Immunol. 2018 Jan;120(1):10-22.e2. doi: 10.1016/j.anai.2017.10.039.
10
Diagnosis and management of moderate to severe adult atopic dermatitis: a Consensus by the Italian Society of Dermatology and Venereology (SIDeMaST), the Italian Association of Hospital Dermatologists (ADOI), the Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC), and the Italian Society of Allergological, Environmental and Occupational Dermatology (SIDAPA).中度至重度成人特应性皮炎的诊断与管理:意大利皮肤病与性病学会(SIDeMaST)、意大利医院皮肤科医生协会(ADOI)、意大利过敏、哮喘与临床免疫学学会(SIAAIC)以及意大利变应性、环境与职业皮肤病学会(SIDAPA)的共识
G Ital Dermatol Venereol. 2018 Apr;153(2):133-145. doi: 10.23736/S0392-0488.17.05892-8. Epub 2017 Dec 14.

在麦德林、安蒂奥基亚及其大都市区的皮肤科教学诊所就诊的特应性皮炎患者的临床和社会人口学特征及生活质量。

Clinical and sociodemographic features and quality of life in patients with atopic dermatitis who attended dermatology teaching clinics in Medellín, Antioquia and its metropolitan area.

机构信息

Facultad de Medicina, Sección Dermatología, Universidad de Antioquia, Medellín, Colombia.

Grupo de Investigación Dermatológica, Universidad de Antioquia, Medellín, Colombia.

出版信息

Biomedica. 2021 Dec 15;41(4):676-691. doi: 10.7705/biomedica.5978.

DOI:10.7705/biomedica.5978
PMID:34936253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8765345/
Abstract

Introduction: Atopic dermatitis is a cutaneous, inflammatory, chronic disease, very frequent in the world and it imposes a high clinical and quality of life impact in patients. To date there are no local studies describing the general features in our population. Objective: To evaluate the socio demographic, clinical and life quality features in patients with atopic dermatitis from Medellín city and its metropolitan area. Materials and methods: cross sectional, descriptive study, that included patients who attended some teaching dermatological clinics. Data collection included sociodemographic and clinical features in addition to clinical issues and quality of life measurements. Results: A total of 13 patients were included. 36,3% manifested a sleeping disturbance, 38,1% attention deficit; 44,2% reported asthma in the childhood. EASI and SCORAD scores were 6,9 and 32,4, respectively, which indicates a mild-moderate compromise. Regarding quality of Life, Skindex-29 showed average scores for the symptomatic, emotional and functional dominions of 37,7, 25,09 and 16,9, respectively, and a total score of 24,78. In EQ-5D scores, the most altered component was the presence of pain or discomfort (17,6%) and the presence of anxiety or depression (12,1%), which enhances the symptomatic and emotional impact of the disease. Conclusion: These results confirm that patients with atopic dermatitis present similar features to those reported in other studies from different countries, highlighting the burden of the disease in adults and its impact in neuropsychiatric and emotional domains.

摘要

简介

特应性皮炎是一种皮肤炎症性慢性疾病,在全球非常普遍,对患者的临床和生活质量都有很大影响。迄今为止,尚无描述我们人群一般特征的本地研究。目的:评估麦德林市及其大都市区特应性皮炎患者的社会人口统计学、临床和生活质量特征。材料和方法:这是一项横断面描述性研究,纳入了一些教学皮肤科诊所就诊的患者。数据收集包括社会人口统计学和临床特征,以及临床问题和生活质量测量。结果:共纳入 13 名患者。36.3%的患者有睡眠障碍,38.1%的患者有注意力缺陷;44.2%的患者在儿童时期有哮喘。EASI 和 SCORAD 评分分别为 6.9 和 32.4,表明病情为轻度至中度。在生活质量方面,Skindex-29 在症状、情绪和功能域的平均得分分别为 37.7、25.09 和 16.9,总分为 24.78。在 EQ-5D 评分中,最受影响的部分是疼痛或不适(17.6%)和焦虑或抑郁(12.1%),这增强了疾病的症状和情绪影响。结论:这些结果证实,特应性皮炎患者具有与其他国家的研究报告相似的特征,突出了成人疾病的负担及其对神经精神和情绪领域的影响。