Physics Service of Radiation Oncology Dept., Humanitas Clinical and Research Hospital, Milan-Rozzano, Italy.
Physics Service of Radiation Oncology Dept., Humanitas Clinical and Research Hospital, Milan-Rozzano, Italy.
Phys Med. 2018 May;49:139-146. doi: 10.1016/j.ejmp.2017.08.007. Epub 2017 Sep 9.
Nanochambers present some advantages in terms of energy independence and absolute dose measurement for small field dosimetry in the SBRT scenario. Characterization of a micro-chamber prototype was carried out both under flattened and flattening-filter-free (FFF) beams with particular focus on stem effect.
The study included characterization of leakage and stem effects, dose rate and dose per pulse dependence, measurement of profiles, and percentage depth doses (PDDs). Ion collection efficiency and polarity effects were measured and evaluated against field size and dose per pulse. The 6_MV, 6_MV_FFF and 10_MV FFF beams of a Varian EDGE were used. Output factors were measured for field sizes ranging from 0.8×0.8cm to 20×20cm and were compared with other detectors.
The 2mm diameter of this chamber guarantees a high spatial resolution with low penumbra values. In orthogonal configuration a strong stem (and cable) effect was observed for small fields. Dose rate and dose per pulse dependence were <0.3% and 0.6% respectively for the whole range of considered values. The Nanochamber exhibits a field size (FS) dependence of the polarity correction >2%. The OF values were compared with other small field detectors showing a good agreement for field sizes >2×2cm. The large field over-response was corrected applying k(FS).
Nanochamber is an interesting option for small field measurements. The spherical shape of the active volume is an advantage in terms of reduced angular dependence. An interesting feature of the Nanochamber is its beam quality independence and, as a future development, the possibility to use it for small field absolute dosimetry.
纳米室在 SBRT 场景中小野绝对剂量测量的能量独立性和绝对剂量测量方面具有一些优势。对微室原型进行了扁平化和无平坦化滤过(FFF)束的特性研究,特别关注了茎效应。
研究包括泄漏和茎效应、剂量率和剂量脉冲依赖性、轮廓和百分深度剂量(PDD)的测量。测量并评估了离子收集效率和极性效应与射野大小和剂量脉冲的关系。使用了瓦里安 EDGE 的 6_MV、6_MV_FFF 和 10_MV_FFF 射线。测量了从 0.8×0.8cm 到 20×20cm 的射野大小的输出因子,并与其他探测器进行了比较。
该室的 2mm 直径保证了高空间分辨率和低半影值。在正交配置下,对于小射野,观察到强烈的茎(和电缆)效应。在考虑的整个值范围内,剂量率和剂量脉冲依赖性分别小于 0.3%和 0.6%。Nanochamber 表现出大于 2%的极性校正的射野大小依赖性。与其他小射野探测器的 OF 值进行了比较,对于大于 2×2cm 的射野,显示出很好的一致性。大射野的过响应通过 k(FS)进行了校正。
Nanochamber 是小野测量的一个有趣选择。活性体积的球形形状在减少角度依赖性方面具有优势。Nanochamber 的一个有趣特点是其束质独立性,并且作为未来的发展,有可能将其用于小野绝对剂量测量。