Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University.
Clin Infect Dis. 2013 Dec;57(11):1600-6. doi: 10.1093/cid/cit555. Epub 2013 Sep 6.
Campylobacteriosis in humans, caused by Campylobacter jejuni and Campylobacter coli, is the most common recognized bacterial zoonosis in the European Union and the United States. The acute phase is characterized by gastrointestinal symptoms. The long-term sequelae (Guillain-Barré syndrome, reactive arthritis, and postinfectious irritable bowel syndrome) contribute considerably to the disease burden. Attribution studies identified poultry as the reservoir responsible for up to 80% of the human Campylobacter infections. In the European Union, an estimated 30% of the human infections are associated with consumption and preparation of poultry meat. Until now, interventions in the poultry meat production chain have not been effectively introduced except for targeted interventions in Iceland and New Zealand. Intervention measures (eg, biosecurity) have limited effect or are hampered by economic aspects or consumer acceptance. In the future, a multilevel approach should be followed, aiming at reducing the level of contamination of consumer products rather than complete absence of Campylobacter.
人类感染弯曲菌病，由空肠弯曲菌和大肠弯曲菌引起，是欧盟和美国最常见的细菌性人畜共患病。急性期的特征是胃肠道症状。长期后遗症（格林-巴利综合征、反应性关节炎和感染后肠易激综合征）对疾病负担有很大影响。归因研究将家禽确定为负责高达 80%人类弯曲菌感染的储存宿主。在欧盟，估计有 30%的人类感染与食用和准备禽肉有关。到目前为止，除了冰岛和新西兰的有针对性干预外，家禽肉生产链中的干预措施并未得到有效实施。干预措施（例如生物安全）的效果有限，或者受到经济方面或消费者接受程度的阻碍。在未来，应该采取多层次的方法，旨在降低消费者产品的污染水平，而不是完全消除弯曲菌。
