Owczarczyk-Saczonek Agnieszka, Wociór Anna, Placek Waldemar, Maksymowicz Wojciech, Wojtkiewicz Joanna
Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Foundation for Nerve Cell Regeneration, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Stem Cells Int. 2017;2017:4740709. doi: 10.1155/2017/4740709. Epub 2017 Aug 21.
The promising results derived from the use of adipose-derived stem cells (ADSCs) in many diseases are a subject of observation in preclinical studies. ADSCs seem to be the ideal cell population for the use in regenerative medicine due to their easy isolation, nonimmunogenic properties, multipotential nature, possibilities for differentiation into various cell lines, and potential for angiogenesis. This article reviews the current data on the use of ADSCs in the treatment of vitiligo, various types of hair loss, and the healing of chronic wounds.
在许多疾病中使用脂肪来源干细胞(ADSCs)所取得的有前景的结果是临床前研究中观察的对象。由于其易于分离、非免疫原性特性、多能性本质、分化为各种细胞系的可能性以及血管生成潜力,ADSCs似乎是再生医学中使用的理想细胞群体。本文综述了目前关于ADSCs在白癜风、各种类型脱发以及慢性伤口愈合治疗中应用的数据。