Sensen B, Braune S, de Heer G, Bein T, Kluge S
Klinik für Intensivmedizin, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
IV. Medizinische Klinik - Internistische Intensivmedizin und Notaufnahme, St. Franziskus-Hospital Münster, Münster, Deutschland.
Med Klin Intensivmed Notfmed. 2017 Oct;112(7):605-611. doi: 10.1007/s00063-017-0350-5. Epub 2017 Sep 13.
Patients who survive acute respiratory distress syndrome (ARDS) often suffer from long-term physical and psychological sequelae. Lung function is commonly only mildly reduced, whereas general physical activity and walking distance are often compromised. Most markedly, these patients have a high incidence of depression, anxiety, and posttraumatic stress disorder. The rate of cognitive dysfunction is as high as 70-100% at the time of hospital discharge, and remains 46-80% and 20% one year and five years post discharge, respectively. The possibility of returning to work is markedly limited. Because of these outcomes, preventative strategies must be identified to reduce the high prevalence of physical and psychological morbidity. Prevention and treatment of delirium as well as early and consequent mobilization and intensive care unit diaries are potentially beneficial.
在急性呼吸窘迫综合征(ARDS)中存活下来的患者常常遭受长期的身体和心理后遗症。肺功能通常仅轻度降低,而一般身体活动和行走距离往往受到影响。最明显的是,这些患者中抑郁症、焦虑症和创伤后应激障碍的发生率很高。出院时认知功能障碍的发生率高达70 - 100%,出院后1年和5年时分别仍为46 - 80%和20%。重返工作岗位的可能性明显受限。鉴于这些结果,必须确定预防策略以降低身体和心理疾病的高患病率。谵妄的预防和治疗以及早期并持续的活动和重症监护病房日志可能有益。