医生请注意：摄入苦杏仁苷片会导致严重氰化物中毒。
Physician Beware: Severe Cyanide Toxicity from Amygdalin Tablets Ingestion.
作者信息
Dang Tam, Nguyen Cham, Tran Phu N
机构信息
Department of Emergency Medicine, Corona Regional Medical Center, Corona, CA, USA.
Department of Pharmacy, University of California Irvine, Orange, CA, USA.
出版信息
Case Rep Emerg Med. 2017;2017:4289527. doi: 10.1155/2017/4289527. Epub 2017 Aug 24.
Despite the risk of cyanide toxicity and lack of efficacy, amygdalin is still used as alternative cancer treatment. Due to the highly lethal nature of cyanide toxicity, many patients die before getting medical care. Herein, we describe the case of a 73-year-old female with metastatic pancreatic cancer who developed cyanide toxicity from taking amygdalin. Detailed history and physical examination prompted rapid clinical recognition and treatment with hydroxocobalamin, leading to resolution of her cyanide toxicity. Rapid clinical diagnosis and treatment of cyanide toxicity can rapidly improve patients' clinical outcome and survival. Inquiries for any forms of ingestion should be attempted in patients with clinical signs and symptoms suggestive of poisoning.
尽管存在氰化物中毒风险且疗效不佳，但苦杏仁苷仍被用作癌症替代疗法。由于氰化物中毒具有高度致命性，许多患者在获得医疗救治前就已死亡。在此，我们描述了一例73岁转移性胰腺癌女性患者，因服用苦杏仁苷发生氰化物中毒的病例。详细的病史和体格检查促使临床迅速识别并采用羟钴胺进行治疗，从而使她的氰化物中毒症状得到缓解。对氰化物中毒进行快速临床诊断和治疗可迅速改善患者的临床结局和生存率。对于有中毒相关临床症状和体征的患者，应尝试询问其是否有任何形式的摄入情况。
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