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三原核胚胎移植后的活产：作为微阵列和延时技术组合的卵胞浆内单精子注射。

Live birth after transfer of a tripronuclear embryo: An intracytoplasmic sperm injection as a combination of microarray and time-lapse technology.

作者信息

Yalçınkaya Ender, Özay Alev, Ergin Elif G, Öztel Zeynep, Özörnek Hakan

机构信息

Eurofertil In Vitro Fertilization Center, Embryology Laboratory, İstanbul, Turkey.

出版信息

Turk J Obstet Gynecol. 2016 Jun;13(2):95-98. doi: 10.4274/tjod.45144. Epub 2016 Jun 15.

DOI:10.4274/tjod.45144
PMID:28913100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5558346/
Abstract

Although around 1-4% of human zygotes have been found to be tripronuclear, there is little information about the subsequent development and chromosomal composition of embryos that derive from these zygotes. Herein, we report a pregnancy and subsequent delivery of a healthy newborn after the transfer of a blastocyst that developed from a tripronuclear zygote that had a euploid microarray result.

摘要

尽管已发现约1%-4%的人类受精卵为三原核，但关于源自这些受精卵的胚胎的后续发育和染色体组成的信息却很少。在此，我们报告了一例妊娠情况，以及在移植了一个由三原核受精卵发育而来且微阵列结果为整倍体的囊胚后，成功分娩出一名健康新生儿的案例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7578/5558346/7780d5cb5aa5/TJOD-13-95-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7578/5558346/b67d7afd43e6/TJOD-13-95-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7578/5558346/7780d5cb5aa5/TJOD-13-95-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7578/5558346/b67d7afd43e6/TJOD-13-95-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7578/5558346/7780d5cb5aa5/TJOD-13-95-g3.jpg

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本文引用的文献

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Reprod Biomed Online. 2012 Oct;25(4):371-81. doi: 10.1016/j.rbmo.2012.06.017. Epub 2012 Jul 7.
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从用冻干精子受精的小鼠二细胞胚胎中提取和分析微核。
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Evaluating the developmental potential of 2.1PN-derived embryos and associated chromosomal analysis.评估 2.1PN 来源胚胎的发育潜能及相关染色体分析。
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