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宫颈鳞状细胞癌早期外阴及脐部切口瘢痕复发：比通常预期的更早。

Early vulvar and umbilical incisional scar recurrence of cervical squamous cell carcinoma: Earlier than usually expected.

作者信息

Özcan Hüseyin Çağlayan, Mustafa Aynur, Bozdağ Zehra, Sucu Seyhun, Uğur Mete Gürol, Balat Özcan

机构信息

Gaziantep University Faculty of Medicine, Department of Obstetrics and Gynecology, Gaziantep, Turkey.

Gaziantep University Faculty of Medicine, Department of Pathology, Gaziantep, Turkey.

出版信息

Turk J Obstet Gynecol. 2017 Jun;14(2):141-144. doi: 10.4274/tjod.40225. Epub 2017 Jun 15.

DOI:10.4274/tjod.40225
PMID:28913152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5558416/
Abstract

Cutaneous metastasis is considered as a hazardous condition depending on the mean survival around 9 months, which usually originates from cancers of the breast, lung, ovary, colon, and rarely from the cervix. The crucial prognostic factor of cutaneous metastasis depends on the period between the primary malignancy and cutaneous metastasis. We report two cases of the unusual presentation of squamous cell cancer of the cervix that developed vulvar and umbilical metastasis in the 5 month of primary treatment. Both of our patients survived for 11 months following the primary treatment. In addition, our first case is the earliest vulvar recurrence of cervical carcinoma in the English literature following appropriate medical and surgical management.

摘要

皮肤转移被认为是一种危险的情况，其平均生存期约为9个月，通常起源于乳腺癌、肺癌、卵巢癌、结肠癌，很少起源于宫颈癌。皮肤转移的关键预后因素取决于原发性恶性肿瘤与皮肤转移之间的时间间隔。我们报告了两例宫颈癌不寻常表现的病例，在初次治疗5个月后出现了外阴和脐部转移。我们的两名患者在初次治疗后均存活了11个月。此外，我们的首例病例是英国文献中经适当药物和手术治疗后最早出现的外阴复发性宫颈癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/e1a0391aaae2/TJOD-14-141-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/4830bc2427ed/TJOD-14-141-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/0b86ae4e2044/TJOD-14-141-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/e1a0391aaae2/TJOD-14-141-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/4830bc2427ed/TJOD-14-141-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/0b86ae4e2044/TJOD-14-141-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71fe/5558416/e1a0391aaae2/TJOD-14-141-g4.jpg

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本文引用的文献

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Sister Mary Joseph Nodule: A Rare Presentation of Squamous Cell Carcinoma of the Cervix.玛丽·约瑟夫修女结节：子宫颈鳞状细胞癌的罕见表现。
Ochsner J. 2015 Fall;15(3):256-8.
2
Cutaneous umbilical metastases in post-menopausal females with gynaecological malignancies.绝经后女性妇科恶性肿瘤的皮肤脐转移
J Turk Ger Gynecol Assoc. 2012 Sep 1;13(3):204-7. doi: 10.5152/jtgga.2012.29. eCollection 2012.
3
Cutaneous metastasis of cervical adenocarcinoma to the vulva.宫颈腺癌皮肤转移至外阴。
玛丽·约瑟夫结节的放射治疗：综述
Adv Radiat Oncol. 2023 Jul 23;9(2):101321. doi: 10.1016/j.adro.2023.101321. eCollection 2024 Feb.
4
Successful management of cutaneous lymphangitis carcinomatosa arising from cervical cancer with paclitaxel-cisplatin and bevacizumab combination therapy: a case report and review of the literature.紫杉醇-顺铂联合贝伐单抗治疗宫颈癌所致皮肤淋巴管癌性炎的成功管理：一例报告并文献复习
J Med Case Rep. 2019 Nov 7;13(1):328. doi: 10.1186/s13256-019-2262-x.
Dermatol Online J. 2013 May 15;19(5):18172.
4
Vulval metastasis from squamous cell carcinoma of the cervix clinically presenting as lymphangioma circumscriptum.宫颈鳞状细胞癌的外阴转移临床上表现为局限性淋巴管瘤。
Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S64-7. doi: 10.5021/ad.2011.23.S1.S64. Epub 2011 Sep 30.
5
Multiple skin metastases to vulva from carcinoma of the cervical stump.宫颈残端癌的外阴多发皮肤转移瘤。
Ginekol Pol. 2010 Feb;81(2):140-3.
6
Umbilical surgical scar and vulval metastasis secondary to advanced cervical squamous cell carcinoma: a report of two cases.脐部手术瘢痕和外阴转移继发于晚期宫颈鳞状细胞癌：两例报告。
Arch Gynecol Obstet. 2010 Apr;281(4):761-4. doi: 10.1007/s00404-009-1235-5. Epub 2009 Sep 30.
7
Peritoneal metastasis in primary cervical cancer: a case report.原发性宫颈癌腹膜转移：一例报告
Eur J Gynaecol Oncol. 2007;28(3):225-8.
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