Zhang Congyan, Liu Pingsheng
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.
Protein Cell. 2017 Nov;8(11):796-800. doi: 10.1007/s13238-017-0467-6. Epub 2017 Sep 14.
The lipid droplet (LD) is a unique multi-functional organelle that contains a neutral lipid core covered with a phospholipid monolayer membrane. The LDs have been found in almost all organisms from bacteria to humans with similar shape. Several conserved functions of LDs have been revealed by recent studies, including lipid metabolism and trafficking, as well as nucleic acid binding and protection. We summarized these findings and proposed a hypothesis that the LD is a conserved organelle.
脂滴（LD）是一种独特的多功能细胞器，其包含一个被磷脂单层膜覆盖的中性脂质核心。几乎在从细菌到人类的所有生物体中都发现了形状相似的脂滴。最近的研究揭示了脂滴的几种保守功能，包括脂质代谢和运输，以及核酸结合和保护。我们总结了这些发现，并提出了一个假说，即脂滴是一种保守的细胞器。
