七氟醚快速麻醉诱导期间额外一氧化二氮的影响。

The influence of additional nitrous oxide during rapid anesthetic induction with sevoflurane.

作者信息

Yurino Masaki, Kimura Hitomi

机构信息

Department of Anesthesiology and Resuscitology, Asahikawa Medical College, 4-5-3-11 Nishikagura, 078, Asahikawa, Hokkaido, Japan.

出版信息

J Anesth. 1994 Dec;8(4):406-409. doi: 10.1007/BF02514617.

DOI:10.1007/BF02514617

PMID:28921346

Abstract

In this study, a vital capacity rapid inhalation induction technique was used, and 4.5% sevoflurane in 100% oxygen and with 66% nitrous oxide in oxygen were compared. Each anesthetic gas was used on a group of 17 unpre-medicated volunteers. The induction time of sevoflurane in nitrous oxide with oxygen and sevoflurane in oxygen were 55±10 s and 81±22 s (SD), respectively, (P<0.05). Notable cardiovascular instability was not observed in either group. Serious complications such as laryngospasm, breath holding, and excessive salivation were not observed in either group. In conclusion, the addition of nitrous oxide to sevoflurane in oxygen is a useful technique because there were no increases in complications during the accelerated rapidity of induction.

摘要

在本研究中，采用肺活量快速吸入诱导技术，对100%氧气中含4.5%七氟醚以及氧气中含66%氧化亚氮的情况进行了比较。每组17名未用药的志愿者使用一种麻醉气体。七氟醚在氧化亚氮与氧气混合气体中以及七氟醚在纯氧中的诱导时间分别为55±10秒和81±22秒（标准差），（P<0.05）。两组均未观察到明显的心血管不稳定情况。两组均未观察到喉痉挛、屏气和唾液分泌过多等严重并发症。总之，在氧气中七氟醚添加氧化亚氮是一种有用的技术，因为在加速诱导过程中并发症并未增加。