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DNA修复途径在癌症生物学与治疗中的影响

The Impact of DNA Repair Pathways in Cancer Biology and Therapy.

作者信息

Nikolaev Anatoly, Yang Eddy S

机构信息

Department of Radiation Oncology, UAB Comprehensive Cancer Center, Birmingham, AL 35249, USA.

出版信息

Cancers (Basel). 2017 Sep 19;9(9):126. doi: 10.3390/cancers9090126.

DOI:10.3390/cancers9090126
PMID:28925933
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5615341/
Abstract

Genomic instability is one of the key hallmarks of cancer progression [1].[...].

摘要

基因组不稳定是癌症进展的关键标志之一[1]。[...]

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本文引用的文献

1
Understanding Resistance Mechanisms and Expanding the Therapeutic Utility of PARP Inhibitors.了解PARP抑制剂的耐药机制并拓展其治疗用途
Cancers (Basel). 2017 Aug 22;9(8):109. doi: 10.3390/cancers9080109.
2
The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer.核心非同源末端连接因子在致癌作用和癌症中的作用
Cancers (Basel). 2017 Jul 6;9(7):81. doi: 10.3390/cancers9070081.
3
Carbon Ion Radiotherapy: A Review of Clinical Experiences and Preclinical Research, with an Emphasis on DNA Damage/Repair.碳离子放射治疗：临床经验与临床前研究综述，重点关注DNA损伤/修复
Cancers (Basel). 2017 Jun 9;9(6):66. doi: 10.3390/cancers9060066.
4
Bridging Plant and Human Radiation Response and DNA Repair through an In Silico Approach.通过计算机模拟方法搭建植物与人类辐射反应及DNA修复之间的桥梁
Cancers (Basel). 2017 Jun 6;9(6):65. doi: 10.3390/cancers9060065.
5
Chemotherapeutic Drugs: DNA Damage and Repair in Glioblastoma.化疗药物：胶质母细胞瘤中的DNA损伤与修复
Cancers (Basel). 2017 May 26;9(6):57. doi: 10.3390/cancers9060057.
6
MTH1 as a Chemotherapeutic Target: The Elephant in the Room.MTH1作为一种化疗靶点：房间里的大象（指被忽视的重要问题）
Cancers (Basel). 2017 May 8;9(5):47. doi: 10.3390/cancers9050047.
7
Targeting the ATR-CHK1 Axis in Cancer Therapy.癌症治疗中靶向 ATR-CHK1 轴
Cancers (Basel). 2017 Apr 27;9(5):41. doi: 10.3390/cancers9050041.
8
DNA Repair Pathway Alterations in Bladder Cancer.膀胱癌中的DNA修复途径改变
Cancers (Basel). 2017 Mar 27;9(4):28. doi: 10.3390/cancers9040028.
9
Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy.试验观察：靶向ATM-CHK2和ATR-CHK1通路进行抗癌治疗
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Cancer stem cells and signaling pathways in radioresistance.癌症干细胞与放射抗性中的信号通路。
Oncotarget. 2016 Mar 8;7(10):11002-17. doi: 10.18632/oncotarget.6760.