Koppen I J N, Benninga M A, Singendonk M M J
Department of Gastroenterology & Nutrition, Emma Children's Hospital, AMC, Amsterdam, The Netherlands.
Early Hum Dev. 2017 Nov;114:1-6. doi: 10.1016/j.earlhumdev.2017.09.005. Epub 2017 Sep 18.
Gastrointestinal motility disorders are common in the pediatric population and may affect the entire gastrointestinal tract and can vary from mild to severe conditions. They may clinically manifest as gastro-esophageal reflux symptoms, feeding difficulties and failure to thrive, constipation and diarrhea amongst others. This review first highlights the embryologic development of the gastrointestinal tract, after which the prenatal and neonatal development of gastrointestinal motility is discussed. Normal motility patterns as seen in (preterm) infants are described as a background for the discussion of the most common congenital and acquired motility disorders in infancy. This review specifically focuses on the role of preterm birth on the development of these disorders.
胃肠动力障碍在儿科人群中很常见，可能影响整个胃肠道，病情轻重不一。临床表现可能包括胃食管反流症状、喂养困难、生长发育不良、便秘和腹泻等。本综述首先强调胃肠道的胚胎发育，之后讨论胃肠动力的产前和新生儿发育情况。描述了（早产）婴儿的正常动力模式，作为讨论婴儿期最常见的先天性和获得性动力障碍的背景。本综述特别关注早产在这些疾病发生发展中的作用。
