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硬膜外镇痛与腹横肌平面阻滞镇痛用于下腹部手术患者术后疼痛缓解的比较:一项前瞻性随机研究

Comparison of Epidural Analgesia with Transversus Abdominis Plane Analgesia for Postoperative Pain Relief in Patients Undergoing Lower Abdominal Surgery: A Prospective Randomized Study.

作者信息

Iyer Sadasivan Shankar, Bavishi Harshit, Mohan Chadalavada Venkataram, Kaur Navdeep

机构信息

Department of Anesthesiology and Pain Medicine, M. S. Ramaiah Medical College and Hospitals, Bengaluru, Karnataka, India.

Department of Anesthesiology, Manipal Hospitals, Bengaluru, Karnataka, India.

出版信息

Anesth Essays Res. 2017 Jul-Sep;11(3):670-675. doi: 10.4103/0259-1162.206856.

Abstract

BACKGROUND

Anesthesiologists play an important role in postoperative pain management. For analgesia after lower abdominal surgery, epidural analgesia and ultrasound-guided transversus abdominis plane (TAP) block are suitable options. The study aims to compare the analgesic efficacy of both techniques.

MATERIALS AND METHODS

Seventy-two patients undergoing lower abdominal surgery under spinal anesthesia were randomized to postoperatively receive lumbar epidural catheter (Group E) or ultrasound-guided TAP block (Group T) through intravenous cannulas placed bilaterally. Group E received 10 ml 0.125% bupivacaine stat and 10 ml 8 hourly for 48 h. Group T received 20 ml 0.125% bupivacaine bilaterally stat and 20 ml bilaterally 8 hourly for 48 h. Pain at rest and on coughing, total paracetamol and tramadol consumption were recorded.

RESULTS

Analgesia at rest was comparable between the groups in the first 16 h. At 24 and 48 h, Group E had significantly better analgesia at rest ( = 0.001 and 0.004 respectively). Patients in Group E had significantly higher number of patients with nil or mild pain on coughing at all times. Paracetamol consumption was comparable in both groups, but tramadol consumption was significantly higher in Group T at the end of 48 h ( = 0.001).

CONCLUSION

For lower abdominal surgeries, analgesia provided by intermittent boluses of 0.125% is comparable for first 16 h between epidural and TAP catheters. However, the quality of analgesia provided by the epidural catheter is superior to that provided by TAP catheters beyond that both at rest and on coughing with reduced opioid consumption.

摘要

背景

麻醉医生在术后疼痛管理中发挥着重要作用。对于下腹部手术后的镇痛,硬膜外镇痛和超声引导下腹横肌平面(TAP)阻滞是合适的选择。本研究旨在比较这两种技术的镇痛效果。

材料与方法

72例在脊麻下接受下腹部手术的患者被随机分为术后通过双侧放置的静脉套管接受腰段硬膜外导管(E组)或超声引导下TAP阻滞(T组)。E组即刻给予10 ml 0.125%布比卡因,随后每8小时给予10 ml,共48小时。T组双侧即刻给予20 ml 0.125%布比卡因,随后每8小时双侧给予20 ml,共48小时。记录静息和咳嗽时的疼痛情况、对乙酰氨基酚和曲马多的总消耗量。

结果

两组在前16小时静息镇痛效果相当。在24小时和48小时时,E组静息镇痛效果明显更好(分别为P = 0.001和0.004)。E组患者在任何时候咳嗽时无痛或轻度疼痛的人数明显更多。两组对乙酰氨基酚的消耗量相当,但在48小时结束时T组曲马多的消耗量明显更高(P = 0.001)。

结论

对于下腹部手术,0.125%布比卡因间歇性推注在硬膜外导管和TAP导管之间前16小时的镇痛效果相当。然而,硬膜外导管提供的镇痛质量优于TAP导管,在静息和咳嗽时均如此,且阿片类药物消耗量减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7da/5594788/0e3621262a17/AER-11-670-g001.jpg

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