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超声引导下双侧竖脊肌平面阻滞与腹横肌平面阻滞用于全腹子宫切除术后镇痛的随机对照研究

Randomized Comparative Study Between Bilateral Erector Spinae Plane Block and Transversus Abdominis Plane Block Under Ultrasound Guidance for Postoperative Analgesia After Total Abdominal Hysterectomy.

作者信息

Shukla Usha, Yadav Urvashi, Singh Amit K, Tyagi Abhishek

机构信息

Anaesthesiology and Critical Care, Uttar Pradesh University of Medical Sciences, Etawah, IND.

Anaesthesiology, Uttar Pradesh University of Medical Sciences, Etawah, IND.

出版信息

Cureus. 2022 May 22;14(5):e25227. doi: 10.7759/cureus.25227. eCollection 2022 May.

Abstract

INTRODUCTION

Ultrasound-guided erector spinae plane (ESP) block has emerged as an effective and safe analgesic regional technique and it also provides visceral pain relief. Our aim was to compare the analgesic efficacy of ESP block over transversus abdominis plane (TAP) block under ultrasound guidance following a total abdominal hysterectomy.

METHODS

This was a prospective, randomized, comparative study. Thirty females posted for elective open total abdominal hysterectomy under general anesthesia were randomly allocated into two groups. Ultrasound-guided ESP block was applied in group E at the T-9 level bilaterally. The study solution was prepared by mixing 20 ml of 0.5% bupivacaine plus 10 ml of 2% lignocaine and 1 ml (50mcg) of fentanyl and 9 ml of normal saline forming total 40 ml of which 20 ml was injected on each side. Group T received ultrasound-guided TAP block with 20 ml of study solution bilaterally. The study solution was prepared similarly by mixing 20 ml of 0.5% bupivacaine plus 10 ml of 2% lignocaine and 1 ml (50mcg) of fentanyl and 9 ml of normal saline (total 40 ml) of which 20 ml was injected into each side. Tramadol 100mg iv was given as rescue analgesia whenever NRS ≥ 4 or on-demand in the postoperative period. The primary outcome was changes in a numerical rating scale (NRS) pain score postoperatively between two groups in 24 h, duration of analgesia and total rescue analgesic required during 24 h. The secondary outcome was patient satisfaction level and side effects if any.

RESULTS

Demographic data were comparable in both groups. The NRS pain score was significantly lower ​​​​in group E than in group T at second, third, fourth, fifth (p < 0.001) and at sixth hour (p < 0.05) postoperatively. The mean duration of analgesia was significantly more in Group E (4.73±0.7 h) compared to group T (2.60±0.51 h) (p < 0.001). The tramadol consumption was seen significantly more in 24 h in group T (233.33±25.82 mg) than in group E (193.33±17.59 mg). Patient satisfaction score was significantly higher at 12 h with mean value of 6.07±0.26 in group E compared to 3.40±0.91 in group T.

CONCLUSION

We conclude that ultrasound-guided ESP block provide better postoperative pain control and prolonged duration of analgesia with less tramadol consumption compared to ultrasound-guided TAP block in patients after total abdominal hysterectomy.

摘要

引言

超声引导下竖脊肌平面(ESP)阻滞已成为一种有效且安全的区域镇痛技术,它还能缓解内脏疼痛。我们的目的是比较全腹子宫切除术后超声引导下ESP阻滞与腹横肌平面(TAP)阻滞的镇痛效果。

方法

这是一项前瞻性、随机、对照研究。30例拟行择期全身麻醉下开放性全腹子宫切除术的女性被随机分为两组。E组在T9水平双侧行超声引导下ESP阻滞。研究溶液的配制方法是将20ml 0.5%布比卡因、10ml 2%利多卡因、1ml(50μg)芬太尼和9ml生理盐水混合,总量为40ml,每侧注射20ml。T组双侧接受超声引导下TAP阻滞,注射20ml研究溶液。研究溶液的配制方法类似,将20ml 0.5%布比卡因、10ml 2%利多卡因、1ml(50μg)芬太尼和9ml生理盐水(总量40ml)混合,每侧注射20ml。术后当数字疼痛评分量表(NRS)≥4或按需时,静脉注射100mg曲马多作为补救镇痛。主要观察指标为两组术后24小时内NRS疼痛评分的变化、镇痛持续时间以及24小时内所需的总补救镇痛量。次要观察指标为患者满意度及是否有副作用。

结果

两组的人口统计学数据具有可比性。术后第2、3、4、5小时(p<0.001)和第6小时(p<0.05),E组的NRS疼痛评分显著低于T组。E组的平均镇痛持续时间(4.73±0.7小时)显著长于T组(2.6±0.51小时)(p<0.001)。T组24小时内曲马多的消耗量(233.33±25.82mg)显著高于E组(193.33±17.59mg)。术后12小时,E组患者满意度评分显著高于T组,E组平均值为6.07±0.26,T组为3.40±0.91。

结论

我们得出结论,对于接受全腹子宫切除术的患者,与超声引导下TAP阻滞相比,超声引导下ESP阻滞能提供更好的术后疼痛控制、更长的镇痛持续时间且曲马多消耗量更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a827/9214188/6e059f614a16/cureus-0014-00000025227-i01.jpg

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