Gowda Dinesh, Premalatha V, Imtiyaz D B
Department of Dermatology, Hairline International Hair Clinic, Bengaluru, Karnataka, India.
Int J Trichology. 2017 Jul-Sep;9(3):101-104. doi: 10.4103/ijt.ijt_48_16.
Nutritional deficiencies are known to be associated with hair loss; however, the exact prevalence is not known.
The aim of this study is to evaluate the prevalence of nutritional deficiencies in participants with hair loss.
In this cross-sectional study, 100 enrolled participants were divided into telogen effluvium (TE), male-pattern hair loss (MPHL), and female-pattern hair loss (FPHL) based on the type of hair loss. All participants underwent laboratory estimation for micronutrients and amino acid levels.
Participants with hair loss showed varied amino acid and micronutrient deficiencies across all types of hair loss. Nutritional status did not vary much between the types of hair loss. Among the essential amino acids, histidine deficiency was seen in >90% of participants with androgenic alopecia and 77.78% of participants with TE while leucine deficiency was seen 98.15% of participants with TE and 100% with FPHL. Valine deficiency was also very common across alopecia subtypes. Among the nonessential amino acids, alanine deficiency was observed in 91.67% FPHL, 91.18% MPHL, and 90.74% TE. Cysteine deficiency was present in 55.58% and 50% of participants with MPHL and TE, respectively. A relatively higher proportion of participants with TE had iron deficiency compared to androgenic alopecia ( = 0.069). Zinc deficiency was seen in 11.76% of participants with MPHL while copper deficiency was seen in 29.41% and 31.48% of participants with MPHL and TE, respectively.
Nutritional deficiency is a common problem in participants with hair loss irrespective of the type of alopecia. The findings of our study suggest need for identification and correction of nutritional deficiencies in patients with hair loss.
已知营养缺乏与脱发有关；然而，确切的患病率尚不清楚。
本研究的目的是评估脱发参与者中营养缺乏的患病率。
在这项横断面研究中，100名登记参与者根据脱发类型分为休止期脱发（TE）、男性型脱发（MPHL）和女性型脱发（FPHL）。所有参与者都接受了微量营养素和氨基酸水平的实验室评估。
脱发参与者在所有类型的脱发中均表现出不同的氨基酸和微量营养素缺乏。营养状况在不同类型的脱发之间变化不大。在必需氨基酸中，>90%的雄激素性脱发参与者和77.78%的TE参与者存在组氨酸缺乏，而98.15%的TE参与者和100%的FPHL参与者存在亮氨酸缺乏。缬氨酸缺乏在各脱发亚型中也很常见。在非必需氨基酸中，91.67%的FPHL、91.18%的MPHL和90.74%的TE参与者存在丙氨酸缺乏。MPHL和TE参与者中分别有55.58%和50%存在半胱氨酸缺乏。与雄激素性脱发相比，TE参与者中铁缺乏的比例相对较高（P = 0.069）。11.76%的MPHL参与者存在锌缺乏，而MPHL和TE参与者中分别有29.41%和31.48%存在铜缺乏。
无论脱发类型如何，营养缺乏都是脱发参与者中的常见问题。我们的研究结果表明，需要对脱发患者进行营养缺乏的识别和纠正。
