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老年人结直肠手术后的第一年

The First Year After Colorectal Surgery in the Elderly.

作者信息

Kornmann Verena N N, van Vugt Jeroen L A, Smits Anke B, van Ramshorst Bert, Boerma Djamila

机构信息

Department of Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.

出版信息

Ann Coloproctol. 2017 Aug;33(4):134-138. doi: 10.3393/ac.2017.33.4.134. Epub 2017 Aug 31.

DOI:10.3393/ac.2017.33.4.134
PMID:28932722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5603342/
Abstract

PURPOSE

Surgery for colorectal malignancy is increasingly being performed in the elderly. Little is known about the impact of complications on late mortality. This study aimed to analyze whether a complicated postoperative course affects the 1-year survival in elderly patients.

METHODS

All consecutive patients older than 75 years of age who underwent colorectal cancer surgery between January 2009 and April 2013 were included in this study. The main outcome was mortality at 1 year after surgery. Logistic regression analyses were performed to determine risk factors for a poor outcome (mortality) after survival of the early postoperative course of surgery at 1-year follow-up. Patients who died within 30 days postoperatively were excluded from analysis.

RESULTS

The early mortality rate was 6.3% (n = 15), and 2 patients died during follow-up as a result of complications after a second surgery. A total of 223 patients survived the perioperative period and were included in this study. Twenty-two patients (9.9%) died during the first year of follow-up. Stage IV disease (P = 0.002), complications of primary surgery (P = 0.016), and comorbidity (P = 0.050) were risk factors for 1-year mortality. Intensive care unit stay, reoperation and readmission were not associated with a worse 1-year outcome.

CONCLUSION

Elderly patients with stage IV disease at the time of surgery, comorbidity, and postoperative complications are at risk for mortality during the first year after surgery. A patient-tailored approach with special attention to perioperative care should be considered in the elderly.

摘要

目的

老年患者接受结直肠癌手术的情况日益增多。关于并发症对晚期死亡率的影响,人们了解甚少。本研究旨在分析术后病程复杂是否会影响老年患者的1年生存率。

方法

本研究纳入了2009年1月至2013年4月期间接受结直肠癌手术的所有连续75岁以上患者。主要结局指标为术后1年的死亡率。进行逻辑回归分析以确定术后早期病程存活至1年随访时预后不良(死亡)的危险因素。术后30天内死亡的患者被排除在分析之外。

结果

早期死亡率为6.3%(n = 15),2例患者在二次手术后因并发症在随访期间死亡。共有223例患者度过围手术期并纳入本研究。22例患者(9.9%)在随访的第一年死亡。IV期疾病(P = 0.002)、初次手术并发症(P = 0.016)和合并症(P = 0.050)是1年死亡率的危险因素。入住重症监护病房、再次手术和再次入院与1年预后较差无关。

结论

手术时处于IV期疾病、合并症以及术后并发症的老年患者在术后第一年有死亡风险。对于老年患者,应考虑采用针对个体的方法并特别关注围手术期护理。

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本文引用的文献

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Curative colorectal resections in patients aged 80 years and older: clinical characteristics, morbidity, mortality and risk factors.80 岁及以上老年患者的结直肠根治性切除术:临床特征、发病率、死亡率和危险因素。
Int J Colorectal Dis. 2013 Jul;28(7):941-7. doi: 10.1007/s00384-012-1626-0. Epub 2012 Dec 15.
2
Comparative outcomes of rectal cancer surgery between elderly and non-elderly patients: a systematic review.老年与非老年直肠癌患者手术治疗效果的比较:系统评价。
Lancet Oncol. 2012 Dec;13(12):e525-36. doi: 10.1016/S1470-2045(12)70378-9.
3
Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference.改善重症监护病房出院后的长期预后:利益相关者会议报告。
Crit Care Med. 2012 Feb;40(2):502-9. doi: 10.1097/CCM.0b013e318232da75.
4
Operative outcomes beyond 30-day mortality: colorectal cancer surgery in oldest old.30 天死亡率以外的手术结果:最年长老年人的结直肠癌手术。
Ann Surg. 2011 May;253(5):947-52. doi: 10.1097/SLA.0b013e318216f56e.
5
Importance of the first postoperative year in the prognosis of elderly colorectal cancer patients.老年结直肠癌患者术后第 1 年对预后的重要性。
Ann Surg Oncol. 2011 Jun;18(6):1533-9. doi: 10.1245/s10434-011-1671-x. Epub 2011 Mar 29.
6
Long-term complications of critical care.危重病长期并发症。
Crit Care Med. 2011 Feb;39(2):371-9. doi: 10.1097/CCM.0b013e3181fd66e5.
7
Caring for octogenarian and nonagenarian patients with colorectal cancer: what should our standards and expectations be?关爱 80 岁及以上的结直肠癌患者:我们的标准和期望应该是什么?
Dis Colon Rectum. 2010 May;53(5):735-43. doi: 10.1007/DCR.0b013e3181cdd658.
8
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9
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10
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