Qiu Yangbo, Shen-Tu Yang
Shanghai Chest Hospital, Shanghai Jiaotong University, Department of Thoracic Surgery, Shanghai Lung Tumor Clinical Medical Center, Shanghai 200039, China.
Zhongguo Fei Ai Za Zhi. 2017 Sep 20;20(9):641-644. doi: 10.3779/j.issn.1009-3419.2017.09.09.
Adenocarcinoma in situ (AIS) is a new concept which was introduced to the 2011 The International Association for the Study of Cancer (IASLC)/ American Thoracic Society (ATS)/ European Respiratory Society (ERS) International Multidisciplinary Classification of Lung Adenocarcinoma firstly and an important supplement of The 2015 World Health Organization Classification of Lung Tumors. Because AIS is at an early stage of development of lung adenocarcinoma, the deepening understanding of its pathology, differential diagnosis, treatment strategies, has an important significance for the improvement of the prognosis of lung adenocarcinoma. This review will provide a systematic review of the main progress of occurrence and development, pathological characteristics, differential diagnosis and treatment strategy of AIS, in order to provide theoretical basis for the further research of AIS.
原位腺癌(AIS)是一个新的概念,它首先被引入到2011年国际肺癌研究协会(IASLC)/美国胸科学会(ATS)/欧洲呼吸学会(ERS)国际多学科肺腺癌分类中,是2015年世界卫生组织肺肿瘤分类的重要补充。由于AIS处于肺腺癌发展的早期阶段,深入了解其病理学、鉴别诊断、治疗策略,对改善肺腺癌的预后具有重要意义。本文将对AIS的发生发展、病理特征、鉴别诊断及治疗策略的主要进展进行系统综述,以便为AIS的进一步研究提供理论依据。