Kohansal Mohammad Hasan, Nourian Abbasali, Rahimi Mohammad Taghi, Daryani Ahmad, Spotin Adel, Ahmadpour Ehsan
Department of Medical Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Acta Trop. 2017 Dec;176:385-394. doi: 10.1016/j.actatropica.2017.09.013. Epub 2017 Sep 19.
Echinococcus granulosus is the causative agent of cystic echinococcosis (CE), which is distributed all around the world. CE is one of the most important global parasitic infectious diseases, both in humans and animals. This parasite causes hydatid cysts that can be lodge at different organs of host such as liver, lung even in heart and brain which may lead to death. Presently, numerous scolicidal chemical agents have been administrated for inactivation of the hydatid cyst contents. Because of increasing resistance and adverse effects of medications include abnormalities of liver function, abdominal pain, diarrhea, nausea, vomiting, dizziness, and headache; there is a need to find alternative therapies either with the least or without side effects. Recently, there is a high tendency among researchers to evaluate and present herbal plants as alternative option due to being inexpensive, easy available, low side effects and toxicity. Till now, many efforts have been conducted on herbal extracts against protoscolices of hydatid cysts throughout the world. Therefore, the current review systematically searched the following electronic databases: PubMed, Science Direct, Scopus, and Google Scholar on published papers according to the keywords. In addition, a comprehensive list of medicinal plants was prepared and some of these herbal plants which showed the best efficacy and promising results are discussed elaborately.
细粒棘球绦虫是囊型包虫病（CE）的病原体，该病在全球范围内均有分布。CE是人类和动物中最重要的全球寄生虫传染病之一。这种寄生虫会导致棘球蚴囊肿，这些囊肿可寄生于宿主的不同器官，如肝脏、肺，甚至心脏和大脑，可能导致死亡。目前，已使用多种杀头节化学药物来灭活棘球蚴囊肿内容物。由于药物的耐药性增加和不良反应，包括肝功能异常、腹痛、腹泻、恶心、呕吐、头晕和头痛，因此需要寻找副作用最小或无副作用的替代疗法。最近，由于草药价格低廉、易于获取、副作用和毒性低，研究人员越来越倾向于评估并将其作为替代选择。到目前为止，全世界已对草药提取物抗棘球蚴囊肿原头节进行了许多研究。因此，本综述根据关键词系统地检索了以下电子数据库：PubMed、Science Direct、Scopus和谷歌学术上的已发表论文。此外，还编制了一份药用植物综合清单，并详细讨论了其中一些显示出最佳疗效和有前景结果的草药。
