Lederman Edith R, Austin Connie, Trevino Ingrid, Reynolds Mary G, Swanson Holly, Cherry Bryan, Ragsdale Jennifer, Dunn John, Meidl Susan, Zhao Hui, Li Yu, Pue Howard, Damon Inger K
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Pediatr Infect Dis J. 2007 Aug;26(8):740-4. doi: 10.1097/INF.0b013e31806211bf.
Orf virus leads to self-limited, subacute cutaneous infections in children who have occupational or recreational contact with infected small ruminants. Breaches in the integument and contact with animals recently vaccinated for orf may be important risk factors in transmission. Common childhood behaviors are likely important factors in the provocation of significant contact (ie, bites) or in unusual lesion location (eg, facial lesions). Clinician recognition is important in distinguishing orf infection from life-threatening cutaneous zoonoses. Recently developed molecular techniques provide diagnostic precision and newer topical therapeutics may hasten healing.
羊痘病毒会导致与受感染的小反刍动物有职业或娱乐接触的儿童发生自限性、亚急性皮肤感染。皮肤破损以及与最近接种过羊痘疫苗的动物接触可能是传播的重要风险因素。常见的儿童行为可能是引发大量接触（如咬伤）或导致病变位置异常（如面部病变）的重要因素。临床医生的识别对于区分羊痘感染与危及生命的皮肤人畜共患病很重要。最近开发的分子技术提供了诊断的精确性，新的局部治疗方法可能会加速愈合。
