Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica.
作者信息
Piccardo P, Ceroni M, Rodgers-Johnson P, Mora C, Asher D M, Char G, Gibbs C J, Gajdusek D C
机构信息
Laboratory of Central Nervous System Studies, National Institute of Neurological and Communicative Disorders and Stroke, Bethesda, MD 20892.
出版信息
Ann Neurol. 1988;23 Suppl:S156-60. doi: 10.1002/ana.410230735.
PMID:2894808
Abstract
The neuropathological examination of the spinal cord of 2 Jamaican patients with classical tropical spastic paraparesis disclosed an intense chronic meningomyelitis with demyelination. In the 1 case in which serum and cerebrospinal fluid were available, antibodies to the human T-lymphotropic virus type 1 were found.
摘要
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