Aboulafia David M
1 Floyd & Delores Jones Cancer Institute at Virginia Mason Medical Center, Seattle, WA, USA.
2 Division of Hematology, University of Washington, Seattle, WA, USA.
Womens Health (Lond). 2017 Dec;13(3):68-79. doi: 10.1177/1745505717731970. Epub 2017 Sep 27.
The number of women living with HIV continues to increase. Thirty years into the AIDS epidemic, we now expect those with access to highly active antiretroviral to survive into their seventh decade of life or beyond. Increasingly, the focus of HIV care is evolving from preventing opportunistic infections and treating AIDS-defining malignancies to strategies that promote longevity. This holistic approach to care includes detection of malignancies that are associated with certain viral infections, with chronic inflammation, and with lifestyle choices. The decision to screen an HIV-infected women for cancer should include an appreciation of the individualized risk of cancer, her life expectancy, and an attempt to balance these concerns with the harms and benefits associated with specific cancer screening tests and their potential outcome. Here, we review cancer screening strategies for women living with HIV/AIDS with a focus on cancers of the lung, breast, cervix, anus, and liver.
感染艾滋病毒的女性人数持续增加。在艾滋病流行30年后,我们现在预计那些能够获得高效抗逆转录病毒治疗的患者能够活到七十多岁甚至更长时间。越来越多的是,艾滋病毒护理的重点正从预防机会性感染和治疗艾滋病相关恶性肿瘤转向促进长寿的策略。这种全面的护理方法包括检测与某些病毒感染、慢性炎症和生活方式选择相关的恶性肿瘤。决定对感染艾滋病毒的女性进行癌症筛查应包括了解个体患癌风险、她的预期寿命,并试图在这些问题与特定癌症筛查测试的危害和益处及其潜在结果之间取得平衡。在此,我们回顾了感染艾滋病毒/艾滋病女性的癌症筛查策略,重点关注肺癌、乳腺癌、宫颈癌、肛门癌和肝癌。