咪达唑仑与替马西泮用于日间手术患者术前用药的比较。
A comparison of midazolam and temazepam for premedication of day case patients.
作者信息
Nightingale J J, Norman J
机构信息
Shackleton Department of Anaesthetics, Southampton General Hospital.
出版信息
Anaesthesia. 1988 Feb;43(2):111-3. doi: 10.1111/j.1365-2044.1988.tb05476.x.
One hundred patients who underwent day case surgery took part in a randomized double-blind comparison between midazolam 15 mg and temazepam 20 mg orally as premedicants. Postoperative recovery was studied using tests of psychomotor function. Midazolam produced a similar degree of anxiolysis to temazepam and a greater incidence of drowsiness. Recovery was similar after either premedicant and psychomotor function was still depressed 4 hours postoperatively (p less than 0.001). Nearly 90% of patients felt that they had benefitted from either premedicant. We conclude that midazolam is a suitable drug for premedication in day case surgery.
100例行日间手术的患者参与了一项随机双盲对照试验，比较口服15毫克咪达唑仑和20毫克替马西泮作为术前用药的效果。使用精神运动功能测试研究术后恢复情况。咪达唑仑产生的抗焦虑程度与替马西泮相似，但嗜睡发生率更高。两种术前用药后的恢复情况相似，术后4小时精神运动功能仍受抑制（p<0.001）。近90%的患者认为他们从两种术前用药中都获益。我们得出结论，咪达唑仑是日间手术术前用药的合适药物。
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