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便秘手术:系统评价和实践建议:结果 III:直肠壁切开术(直肠切开术)。

Surgery for constipation: systematic review and practice recommendations: Results III: Rectal wall excisional procedures (Rectal Excision).

机构信息

Queen Elizabeth Hospital, Gateshead NHS Trust, Gateshead, UK.

National Bowel Research Centre, Blizard Institute, Queen Mary, University London, London, UK.

出版信息

Colorectal Dis. 2017 Sep;19 Suppl 3:49-72. doi: 10.1111/codi.13772.

Abstract

AIM

To assess the outcomes of rectal excisional procedures in adults with chronic constipation.

METHOD

Standardised methods and reporting of benefits and harms were used for all CapaCiTY reviews that closely adhered to PRISMA 2016 guidance. Main conclusions were presented as summary evidence statements with a summative Oxford Centre for Evidence-Based Medicine (2009) level.

RESULTS

Forty-seven studies were identified, providing data on outcomes in 8340 patients. Average length of procedures was 44 min and length of stay (LOS) was 3 days. There was inadequate evidence to determine variations in procedural duration or LOS by type of procedure. Overall morbidity rate was 16.9% (0-61%), with lower rates observed after Contour Transtar procedure (8.9%). No mortality was reported after any procedures in a total of 5896 patients. Although inconsistently reported, good or satisfactory outcome occurred in 73-80% of patients; a reduction of 53-91% in Longo scoring system for obstructive defecation syndrome (ODS) occurred in about 68-76% of patients. The most common long-term adverse outcome is faecal urgency, typically occurring in up to 10% of patients. Recurrent prolapse occurred in 4.3% of patients. Patients with at least 3 ODS symptoms together with a rectocoele with or without an intussusception, who have failed conservative management, may benefit from a rectal excisional procedure.

CONCLUSION

Rectal excisional procedures are safe with little major morbidity. It is not possible to advise which excisional technique is superior from the point of view of efficacy, peri-operative variables, or harms. Future study is required.

摘要

目的

评估直肠切除术治疗成人慢性便秘的疗效。

方法

所有 CapaCiTY 综述均采用标准化方法和效益与危害报告,紧密遵循 PRISMA 2016 指南。主要结论以总结证据陈述的形式呈现,并采用牛津循证医学中心(2009 年)的总结评价级别。

结果

共确定了 47 项研究,提供了 8340 例患者结局的数据。手术平均时长为 44 分钟,住院时间(LOS)为 3 天。但没有足够的证据来确定不同手术类型之间的手术持续时间或 LOS 的变化。总发病率为 16.9%(0-61%),Contour Transtar 手术后发病率较低(8.9%)。在总共 5896 例患者中,没有任何手术报告死亡。尽管报告不一致,但术后 73-80%的患者疗效良好或满意;约 68-76%的患者在长段排便困难评分系统(ODS)中的排便困难评分降低了 53-91%。最常见的长期不良后果是粪便急迫感,通常发生在多达 10%的患者中。复发性脱垂发生在 4.3%的患者中。至少有 3 个 ODS 症状,伴有直肠前突或伴有肠套叠,且保守治疗失败的患者可能受益于直肠切除术。

结论

直肠切除术是安全的,只有轻微的主要发病率。从疗效、围手术期变量或危害的角度来看,无法建议哪种切除技术更优越。需要进一步的研究。

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