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锌状态与炎症、氧化应激、脂质及葡萄糖代谢相关。

Zinc status is associated with inflammation, oxidative stress, lipid, and glucose metabolism.

作者信息

Olechnowicz J, Tinkov A, Skalny A, Suliburska Joanna

机构信息

Poznan University of Life Sciences, ul. Wojska Polskiego 31, 62-624, Poznan , Poland.

Orenburg State Medical University, Sovetskaya St., 6, Orenburg, 460000, Russia.

出版信息

J Physiol Sci. 2018 Jan;68(1):19-31. doi: 10.1007/s12576-017-0571-7. Epub 2017 Sep 30.

DOI:10.1007/s12576-017-0571-7
PMID:28965330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5754376/
Abstract

A number of studies have reported that zinc plays a substantial role in the development of metabolic syndrome, taking part in the regulation of cytokine expression, suppressing inflammation, and is also required to activate antioxidant enzymes that scavenge reactive oxygen species, reducing oxidative stress. Zinc also plays a role in the correct functioning of lipid and glucose metabolism, regulating and forming the expression of insulin. In numerous studies, zinc supplementation has been found to improve blood pressure, glucose, and LDL cholesterol serum level. Deeper knowledge of zinc's properties may help in treating metabolic syndrome, thus protecting against stroke and angina pectoris, and ultimately against death.

摘要

多项研究报告称,锌在代谢综合征的发展中起着重要作用,参与细胞因子表达的调节、抑制炎症,并且激活清除活性氧的抗氧化酶也需要锌,从而降低氧化应激。锌在脂质和葡萄糖代谢的正常运作中也发挥作用,调节并形成胰岛素的表达。在众多研究中,已发现补充锌可改善血压、血糖和低密度脂蛋白胆固醇的血清水平。对锌特性的更深入了解可能有助于治疗代谢综合征,从而预防中风和心绞痛,并最终预防死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/f6e4d30717ae/12576_2017_571_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/9c769b6f462c/12576_2017_571_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/71343d225d20/12576_2017_571_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/f6e4d30717ae/12576_2017_571_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/9c769b6f462c/12576_2017_571_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/71343d225d20/12576_2017_571_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c47/10716998/f6e4d30717ae/12576_2017_571_Fig3_HTML.jpg

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