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PySCeSToolbox:一组代谢途径分析工具。

PySCeSToolbox: a collection of metabolic pathway analysis tools.

机构信息

Department of Biochemistry, Laboratory for Molecular Systems Biology, Stellenbosch University, South Africa.

Centre for Complex Systems in Transition, School of Public Leadership, Stellenbosch University, Stellenbosch 7602, South Africa.

出版信息

Bioinformatics. 2018 Jan 1;34(1):124-125. doi: 10.1093/bioinformatics/btx567.

Abstract

SUMMARY

PySCeSToolbox is an extension to the Python Simulator for Cellular Systems (PySCeS) that includes tools for performing generalized supply-demand analysis, symbolic metabolic control analysis, and a framework for investigating the kinetic and thermodynamic aspects of enzyme-catalyzed reactions. Each tool addresses a different aspect of metabolic behaviour, control, and regulation; the tools complement each other and can be used in conjunction to better understand higher level system behaviour.

AVAILABILITY AND IMPLEMENTATION

PySCeSToolbox is available on Linux, Mac OS X and Windows. It is licensed under the BSD 3-clause licence. Code, setup instructions and a link to documentation can be found at https://github.com/PySCeS/PyscesToolbox.

CONTACT

jr@sun.ac.za.

SUPPLEMENTARY INFORMATION

Supplementary data are available at Bioinformatics online.

摘要

摘要

PySCeSToolbox 是 Python Simulator for Cellular Systems(PySCeS)的扩展,它包含了用于执行广义供需分析、符号代谢控制分析以及用于研究酶催化反应动力学和热力学方面的框架的工具。每个工具都针对代谢行为、控制和调节的不同方面;这些工具相互补充,可以结合使用以更好地理解更高层次的系统行为。

可用性和实现

PySCeSToolbox 可在 Linux、Mac OS X 和 Windows 上使用。它根据 BSD 3 条款许可证获得许可。代码、安装说明和文档链接可在 https://github.com/PySCeS/PyscesToolbox 上找到。

联系人

jr@sun.ac.za

补充信息

补充数据可在 Bioinformatics 在线获得。

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