DistributedFBA.jl：Julia 中用于通量平衡分析的高级高性能工具。
DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia.
作者信息
Heirendt Laurent, Thiele Ines, Fleming Ronan M T
机构信息
University of Luxembourg, Luxembourg Centre for Systems Biomedicine, Esch-sur-Alzette, Luxembourg.
出版信息
Bioinformatics. 2017 May 1;33(9):1421-1423. doi: 10.1093/bioinformatics/btw838.
MOTIVATION
Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.
RESULTS
DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.
AVAILABILITY AND IMPLEMENTATION
The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.
CONTACT
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
动机
通量平衡分析及其变体是预测生化反应网络中稳态反应速率的广泛使用的方法。目前，此类方法在探索高维网络时受到软件性能限制的阻碍。
结果
DistributedFBA.jl是Julia中通量平衡分析的高级、高性能开源实现。它专为在任意数量的线程或节点上对大型和超大规模网络的子集或所有反应进行多个通量平衡分析而设计。
可用性与实现
代码可在github.com/opencobra/COBRA.jl上免费获取。文档可在opencobra.github.io/COBRA.jl上找到。
联系方式
补充信息
补充数据可在《生物信息学》在线版获取。
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