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留置输尿管支架患者输尿管结石的自然排出

Spontaneous passage of ureteral stones in patients with indwelling ureteral stents.

作者信息

Baumgarten Lee, Desai Anuj, Shipman Scott, Eun Daniel D, Pontari Michel A, Mydlo Jack H, Reese Adam C

机构信息

Department of Urology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

出版信息

Can J Urol. 2017 Oct;24(5):9024-9029.

Abstract

INTRODUCTION

To determine rates of spontaneous ureteral stone passage in patients with indwelling ureteral stents, and to identify factors associated with the spontaneous passage of stones while a ureteral stent is in place.

MATERIALS AND METHODS

From our institutional database, we identified patients who underwent ureteroscopic procedures for stone disease between January 1, 2013 and March 1, 2015. We compared the rates of spontaneous stone passage between patients who had previously undergone ureteral stent placement and those who had not. In patients with indwelling stents, multivariate logistic regression was performed to identify factors associated with spontaneous stone passage.

RESULTS

A total of 194 patients met inclusion criteria. Spontaneous stone passage rates were similar in the stented (17/119, 14%) and non-stented (15/75, 20%) groups (p = 0.30). In bivariate analysis of stented patients, smaller stone size (p < 0.001) and distal stone location (p = 0.01) were significantly associated with spontaneous stone passage. Multivariate logistic regression analysis of stented patients showed that only small stone size was significantly associated with the likelihood of stone passage (p = 0.01), whereas stent duration, stone location, and stone laterality were not.

CONCLUSIONS

A small, but clinically significant percentage of ureteral stones pass spontaneously with a ureteral stent in place. Small stone size is associated with an increased likelihood of spontaneous passage in patients with indwelling stents. These findings may help to identify patients who can potentially avoid additional surgical procedures for definitive stone removal after ureteral stent placement.

摘要

引言

确定留置输尿管支架患者输尿管结石的自然排出率,并识别输尿管支架在位时与结石自然排出相关的因素。

材料与方法

从我们机构的数据库中,我们识别出在2013年1月1日至2015年3月1日期间因结石疾病接受输尿管镜手术的患者。我们比较了先前接受输尿管支架置入的患者和未接受该操作的患者之间结石自然排出率。在留置支架的患者中,进行多因素逻辑回归分析以识别与结石自然排出相关的因素。

结果

共有194例患者符合纳入标准。支架置入组(17/119,14%)和未置入支架组(15/75,20%)的结石自然排出率相似(p = 0.30)。在对留置支架患者的二元分析中,较小的结石尺寸(p < 0.001)和结石位于远端(p = 0.01)与结石自然排出显著相关。对留置支架患者的多因素逻辑回归分析显示,只有较小的结石尺寸与结石排出的可能性显著相关(p = 0.01),而支架留置时间、结石位置和结石位于左侧或右侧则无此关联。

结论

一小部分但具有临床意义的输尿管结石在输尿管支架在位时会自然排出。较小的结石尺寸与留置支架患者自然排出的可能性增加相关。这些发现可能有助于识别那些在输尿管支架置入后可能避免额外手术以彻底清除结石的患者。

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