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骨水泥固定技术影响高屈曲度全膝关节置换术后股骨假体松动率。

Cementing technique affects the rate of femoral component loosening after high flexion total knee arthroplasty.

作者信息

Han Hyuk-Soo, Lee Myung Chul

机构信息

Department of Orthopedic Surgery, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.

出版信息

Knee. 2017 Dec;24(6):1435-1441. doi: 10.1016/j.knee.2017.08.002. Epub 2017 Sep 30.

Abstract

BACKGROUND

The purpose of this study was to determine the effects of different cementing techniques on the rate of early femoral loosening of high-flexion total knee arthroplasties (TKAs).

METHODS

A total of 734 knees from 486 patients treated with high-flexion design TKA between July 2001 and July 2010 were divided into two groups based on the cementing technique used. For 403 knees (group N), cement was applied onto the distal and anterior cut surfaces of the femur and the posterior flanges of the femoral component without pressurization. For 331 knees (group P), cement was applied onto distal and anterior femoral cut surfaces with digital pressurization and whole cement surfaces of the femoral component. Two groups were subjected to clinical and radiological evaluation with a minimum five year follow-up period. Cox proportional hazards model with revision surgery of the prosthesis or radiological loosening as an endpoint was used to evaluate the effect of the cementing technique and other covariates.

RESULTS

The pressurizing and bi-surface cementing technique resulted in significant reduction in femoral radiological loosening incidence compared to that without pressurization (0.3% vs. 2.5%, P=0.015) and revision rate for aseptic causes (0.9% vs. 3.2%, P=0.032). Cox proportional hazard regression analysis revealed a significant difference in component survival rate between the two groups if femoral radiological loosening was considered as failure (hazard ratio, 4.229, 95% confidence interval (CI): 1.256-14.243, P=0.020).

CONCLUSION

Pressurizing and bi-surface cementation can reduce the occurrence rate of early loosening around the femoral component in high-flexion TKAs.

摘要

背景

本研究旨在确定不同的骨水泥固定技术对高屈曲度全膝关节置换术(TKA)早期股骨松动率的影响。

方法

将2001年7月至2010年7月间接受高屈曲度设计TKA治疗的486例患者的734个膝关节,根据所使用的骨水泥固定技术分为两组。对于403个膝关节(N组),骨水泥被涂抹在股骨远端和前侧截骨面以及股骨假体的后侧翼上,未进行加压。对于331个膝关节(P组),骨水泥被涂抹在股骨远端和前侧截骨面上,并对股骨假体的整个骨水泥表面进行手指加压。两组均接受了至少五年随访期的临床和影像学评估。以假体翻修手术或影像学松动为终点的Cox比例风险模型用于评估骨水泥固定技术和其他协变量的影响。

结果

与未加压的情况相比,加压和双表面骨水泥固定技术导致股骨影像学松动发生率显著降低(0.3%对2.5%,P = 0.015)以及无菌性原因导致的翻修率降低(0.9%对3.2%,P = 0.032)。如果将股骨影像学松动视为失败,Cox比例风险回归分析显示两组之间的假体生存率存在显著差异(风险比,4.229,95%置信区间(CI):1.256 - 14.243,P = 0.020)。

结论

加压和双表面骨水泥固定可降低高屈曲度TKA中股骨假体周围早期松动的发生率。

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