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本文引用的文献

1
Variability of Diabetes Alert Dog Accuracy in a Real-World Setting.现实环境中糖尿病警报犬准确性的变异性。
J Diabetes Sci Technol. 2017 Jul;11(4):714-719. doi: 10.1177/1932296816685580. Epub 2017 Jan 9.
2
Psychology, technology, and diabetes management.心理学、技术与糖尿病管理。
Am Psychol. 2016 Oct;71(7):577-589. doi: 10.1037/a0040383.
3
Reliability of Trained Dogs to Alert to Hypoglycemia in Patients With Type 1 Diabetes.训练有素的犬类对1型糖尿病患者低血糖发出警报的可靠性。
J Diabetes Sci Technol. 2017 May;11(3):506-512. doi: 10.1177/1932296816666537. Epub 2016 Aug 28.
4
Dogs Can Be Successfully Trained to Alert to Hypoglycemia Samples from Patients with Type 1 Diabetes.狗可以被成功训练来对1型糖尿病患者的低血糖样本发出警报。
Diabetes Ther. 2015 Dec;6(4):509-517. doi: 10.1007/s13300-015-0135-x. Epub 2015 Oct 6.
5
Time Delay of CGM Sensors: Relevance, Causes, and Countermeasures.连续血糖监测(CGM)传感器的时间延迟:相关性、原因及对策
J Diabetes Sci Technol. 2015 Aug 4;9(5):1006-15. doi: 10.1177/1932296815590154.
6
Perceptions about professionally and non-professionally trained hypoglycemia detection dogs.关于专业训练和非专业训练的低血糖检测犬的认知。
Diabetes Res Clin Pract. 2015 Aug;109(2):389-96. doi: 10.1016/j.diabres.2015.05.023. Epub 2015 May 15.
7
Can trained dogs detect a hypoglycemic scent in patients with type 1 diabetes?经过训练的狗能检测出1型糖尿病患者的低血糖气味吗?
Diabetes Care. 2013 Jul;36(7):e98-9. doi: 10.2337/dc12-2342.
8
Evidence of a strong association between frequency of self-monitoring of blood glucose and hemoglobin A1c levels in T1D exchange clinic registry participants.在 T1D 交换诊所注册参与者中,自我监测血糖频率与血红蛋白 A1c 水平之间存在很强关联的证据。
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9
Statistical tools to analyze continuous glucose monitor data.分析连续血糖监测数据的统计工具。
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10
Is the frequency of self-monitoring of blood glucose related to long-term metabolic control? Multicenter analysis including 24,500 patients from 191 centers in Germany and Austria.血糖自我监测频率与长期代谢控制有关吗?对来自德国和奥地利191个中心的24500名患者进行的多中心分析。
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糖尿病警报犬(DADs):准确性及影响评估

Diabetes Alert Dogs (DADs): An assessment of accuracy and implications.

作者信息

Gonder-Frederick Linda A, Grabman Jesse H, Shepard Jaclyn A

机构信息

Behavioral Medicine Center, University of Virginia, Charlottesville, VA 22908, USA.

Behavioral Medicine Center, University of Virginia, Charlottesville, VA 22908, USA.

出版信息

Diabetes Res Clin Pract. 2017 Dec;134:121-130. doi: 10.1016/j.diabres.2017.09.009. Epub 2017 Sep 30.

DOI:10.1016/j.diabres.2017.09.009
PMID:28974470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5723560/
Abstract

AIMS

To test the accuracy of Diabetes Alert Dogs (DADs) by comparing recorded alerts to continuous glucose monitoring (CGM) device readings during waking and sleeping hours.

METHODS

14 individuals (7 adults with type 1 diabetes and 7 youth with type 1 diabetes/parents) who owned DADs for ≥6 mos wore masked CGM devices over a several-week period while recording DAD alerts electronically and in paper diaries.

RESULTS

During waking hours, sensitivity scores across participants were 35.9% for low BG events and 26.2% for high BG events. DAD accuracy was highly variable with 3/14 individual dogs performing statistically higher than chance. Sensitivity scores were lower during sleep hours of the person with diabetes (22.2% for low BG events and 8.4% for high BG events). DAD accuracy during sleeping hours was also highly variable, with 1/11 individual dogs performing statistically better than chance. Rate of change analyses indicated that DADs were responding to absolute BG level, rather than rapid shifts in glucose levels.

CONCLUSIONS

In this study the majority of DADs did not demonstrate accurate detection of low and high BG events. However, performance varied greatly across DADs and additional studies are needed to examine factors contributing to this variability. Additionally, more research is needed to investigate the significant gap between the positive experiences and clinical outcomes reported by DAD owners and the mixed research findings on DAD accuracy.

摘要

目的

通过比较清醒和睡眠期间糖尿病预警犬(DAD)记录的警报与持续葡萄糖监测(CGM)设备读数,测试糖尿病预警犬的准确性。

方法

14名拥有糖尿病预警犬≥6个月的个体(7名1型糖尿病成年患者和7名1型糖尿病青少年/家长)在数周时间内佩戴隐蔽式CGM设备,同时以电子方式和纸质日记记录糖尿病预警犬的警报。

结果

在清醒时间,参与者对低血糖事件的敏感度评分为35.9%,对高血糖事件的敏感度评分为26.2%。糖尿病预警犬的准确性差异很大,14只犬中有3只在统计学上表现高于随机水平。糖尿病患者睡眠期间的敏感度评分较低(低血糖事件为22.2%,高血糖事件为8.4%)。睡眠期间糖尿病预警犬的准确性也差异很大,11只犬中有1只在统计学上表现优于随机水平。变化率分析表明,糖尿病预警犬对血糖绝对水平做出反应,而非葡萄糖水平的快速变化。

结论

在本研究中,大多数糖尿病预警犬并未准确检测出低血糖和高血糖事件。然而,不同糖尿病预警犬的表现差异很大,需要更多研究来探讨导致这种差异的因素。此外,还需要更多研究来调查糖尿病预警犬主人报告的积极体验与临床结果之间的显著差距,以及关于糖尿病预警犬准确性的混合研究结果。