Raineri Santi Maurizio, Cortegiani Andrea, Vitale Filippo, Iozzo Pasquale, Giarratano Antonino
Department of Biopathology and Medical Biotechnologies (DIBIMED). Section of Anesthesia, Analgesia, Intensive Care and Emergency. Policlinico P. Giaccone, University of Palermo, Via del vespro 129, 90127 Palermo, Italy.
J Intensive Care. 2017 Sep 25;5:58. doi: 10.1186/s40560-017-0252-x. eCollection 2017.
Procalcitonin is a widely used marker for the evaluation of infection and sepsis and to guide antibiotic therapy. During the last decade, several studies evaluated its role and diagnostic performance as a surrogate marker for the identification of spp. in suspected invasive candidiasis. A low serum level and a favorable negative predictive value are the main findings for procalcitonin in this setting. The aim of this report is to provide an updated brief summary of the evidence supporting the use of PCT for the management of invasive candidiasis.
降钙素原是一种广泛用于评估感染和脓毒症以及指导抗生素治疗的标志物。在过去十年中,多项研究评估了其作为疑似侵袭性念珠菌病中念珠菌属鉴定替代标志物的作用和诊断性能。在这种情况下,降钙素原的主要发现是血清水平低和阴性预测值良好。本报告的目的是提供一份最新的简要概述,以支持使用降钙素原管理侵袭性念珠菌病的证据。