Brayne C, Calloway P
Department of Community Medicine, Addenbrooke's Hospital, Cambridge.
Lancet. 1988 Jun 4;1(8597):1265-7. doi: 10.1016/s0140-6736(88)92081-8.
There is little evidence to support the view that senile dementia of the Alzheimer's type (SDAT) is distinct from the normal ageing process. The changes in brain function found in normal ageing, benign senescent forgetfulness, and SDAT can be seen as a continuum, which may reflect a single underlying process. The failure to account for this possibility in research design may explain why few risk factors for SDAT have been identified.
几乎没有证据支持阿尔茨海默型老年痴呆症（SDAT）与正常衰老过程不同的观点。在正常衰老、良性衰老遗忘症和SDAT中发现的大脑功能变化可被视为一个连续体，这可能反映了一个单一的潜在过程。在研究设计中未能考虑到这种可能性，可能解释了为什么几乎没有确定SDAT的风险因素。
