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根据 DASH 饮食进行个体化营养治疗对原发性高血压超重/肥胖患者血压、体重和部分生化参数的影响:一项前瞻性随机研究。

The impact of individualised nutritional therapy according to DASH diet on blood pressure, body mass, and selected biochemical parameters in overweight/obese patients with primary arterial hypertension: a prospective randomised study.

机构信息

Department of Human Nutrition, Medical University of Warsaw, Warsaw, Poland

Department of Dietetics, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences, Warsaw, Poland

出版信息

Kardiol Pol. 2018;76(1):158-165. doi: 10.5603/KP.a2017.0184. Epub 2017 Oct 5.

Abstract

BACKGROUND AND AIM

The aim of the study was to assess the impact of individualised nutritional intervention based on the DASH diet (Dietary Approaches to Stop Hypertension) on the nutritional status, blood pressure, and selected biochemical parameters of obese/overweight patients with primary arterial hypertension.

METHODS

A total of 131 participants were randomised to the DASH intervention group (DIG; n = 69, 33 males) or the control group (CG; n = 62, 32 males). A three-month nutritional intervention was carried out in the DIG group, while the control group received only standard recommendations. Body weight, height, waist and hip circumference, body composition, blood pressure, serum glucose, and insulin and leptin concentrations were measured at the baseline and after the intervention.

RESULTS

Sixty-four (92.8%) participants in the intervention and 62 (100%) in the control group completed the study. In the DIG group a significant decrease in body mass, systolic and diastolic blood pressure, body fat content, fasting glucose, insulin, and leptin concentrations were observed in comparison to the control group (p < 0.05).

CONCLUSIONS

The DASH dietary intervention provides significant benefits to overweight/obese patients with primary hypertension.

摘要

背景与目的

本研究旨在评估基于 DASH 饮食(停止高血压的饮食方法)的个体化营养干预对原发性高血压肥胖/超重患者的营养状况、血压和某些生化参数的影响。

方法

共有 131 名参与者被随机分为 DASH 干预组(DIG;n = 69,33 名男性)或对照组(CG;n = 62,32 名男性)。DIG 组进行为期三个月的营养干预,而对照组仅接受标准建议。在基线和干预后测量体重、身高、腰围和臀围、身体成分、血压、血清葡萄糖以及胰岛素和瘦素浓度。

结果

干预组有 64 名(92.8%)参与者和对照组有 62 名(100%)参与者完成了研究。与对照组相比,DIG 组的体重、收缩压和舒张压、体脂肪含量、空腹血糖、胰岛素和瘦素浓度均显著降低(p < 0.05)。

结论

DASH 饮食干预对原发性高血压肥胖/超重患者有显著益处。

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