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眼科领域阿片类药物处方模式与滥用之间的关联

Association Between Opioid Prescribing Patterns and Abuse in Ophthalmology.

作者信息

Patel Shriji, Sternberg Paul

机构信息

Vanderbilt Eye Institute, Nashville, Tennessee.

出版信息

JAMA Ophthalmol. 2017 Nov 1;135(11):1216-1220. doi: 10.1001/jamaophthalmol.2017.4055.

Abstract

IMPORTANCE

Drug overdoses have become the number 1 cause of mortality in American adults 50 years and younger. Prescription opioid abuse is a growing concern that has garnered widespread attention among policymakers and the general public.

OBJECTIVE

To determine the opioid prescribing patterns among ophthalmologists and elucidate their role in the prescription opioid abuse epidemic.

DESIGN, SETTING, AND PARTICIPANTS: In this observational cohort study, beneficiaries and their physicians were analyzed using 2013 to 2015 Medicare Part D Prescriber Data. The Centers for Medicare and Medicaid Services Medicare Part D Prescriber Public Use Files for 2013, 2014, and 2015 were accessed. Analysis began in June 2017. Data were collected and analyzed regarding the prescribing patterns for opioid drugs (eg, number of prescriptions written including refills, number of days' supply, and prescriber rates) for all participating ophthalmologists.

MAIN OUTCOMES AND MEASURES

The mean number of opioid prescriptions written annually by ophthalmologists; prescriber rates compared with all prescriptions written; and geographic distribution of opioid prescriptions written per ophthalmologist.

RESULTS

In 2013, 4167 of 19 615 ophthalmologists were women (21.2%). Consistently, most ophthalmologists (88%-89%) wrote 10 opioid prescriptions or fewer annually. Approximately 1% (0.94%-1.03%) of ophthalmologists wrote more than 100 prescriptions per year. On average, ophthalmologists wrote 7 opioid prescriptions per year (134 290 written annually by 19 638 physicians, on average) with a mean supply of 5 days. The 6 states with the highest volume of opioid prescriptions written annually per ophthalmologist were located in the southern United States.

CONCLUSIONS AND RELEVANCE

In general, ophthalmologists show discretion in their opioid prescribing patterns. The present opioid abuse epidemic should prompt physicians to consider revisiting their prescribing protocols given the high risk for dependency.

摘要

重要性

药物过量已成为50岁及以下美国成年人的首要死因。处方阿片类药物滥用问题日益严重,已引起政策制定者和公众的广泛关注。

目的

确定眼科医生的阿片类药物处方模式,并阐明他们在处方阿片类药物滥用流行中的作用。

设计、背景和参与者:在这项观察性队列研究中,使用2013年至2015年医疗保险D部分处方医生数据对受益人和他们的医生进行分析。获取了医疗保险和医疗补助服务中心2013年、2014年和2015年医疗保险D部分处方医生公共使用文件。分析于2017年6月开始。收集并分析了所有参与研究的眼科医生的阿片类药物处方模式数据(例如,开具的包括续方在内的处方数量、供应天数和处方医生比例)。

主要结局和指标

眼科医生每年开具的阿片类药物处方的平均数量;与开具的所有处方相比的处方医生比例;以及每位眼科医生开具的阿片类药物处方的地理分布。

结果

2013年,19615名眼科医生中有4167名女性(21.2%)。一直以来,大多数眼科医生(88%-89%)每年开具10张或更少的阿片类药物处方。约1%(0.94%-1.03%)的眼科医生每年开具超过100张处方。眼科医生平均每年开具7张阿片类药物处方(19638名医生每年平均开具134290张),平均供应天数为5天。每年每位眼科医生开具阿片类药物处方数量最多的6个州位于美国南部。

结论和意义

总体而言,眼科医生在阿片类药物处方模式上表现出谨慎。鉴于成瘾风险高,当前的阿片类药物滥用流行应促使医生考虑重新审视他们的处方方案。

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