Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
National Institute of Mental Health, NIH, Bethesda, MD, USA.
Cell. 2017 Oct 5;171(2):261-264. doi: 10.1016/j.cell.2017.09.037.
The genetics of African populations reveals an otherwise "missing layer" of human variation that arose between 100,000 and 5 million years ago. Both the vast number of these ancient variants and the selective pressures they survived yield insights into genes responsible for complex traits in all populations.
非洲人群的遗传学揭示了一个原本“缺失的层次”的人类变异,它发生在 10 万至 500 万年前。这些古老变体的数量之多,以及它们所经历的选择压力,都为所有人群中负责复杂特征的基因提供了深入的了解。