Kumar Suresh, Sharma Sunil, Vasudeva Neeru
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, 125001, India.
Laureate Institute of Pharmacy, Kathog, Distt., Kangra, 177101, India.
Chin J Integr Med. 2017 Oct 6. doi: 10.1007/s11655-017-2414-z.
Antioxidants are the substances that are capable of counteracting the damaging effects of the physiological process of oxidation occur in animal tissues. These may be nutrients (vitamins and minerals) as well as enzymes (proteins) in our body that assist in chemical reactions. They are believed to play a role in preventing the development of chronic diseases like cancer, diabetes, heart disease, stroke, Alzheimer's disease, rheumatoid arthritis, and cataracts etc. The present review article emphasizes on the various aspects of oxidants and antioxidants viz. definition, types, causes, mechanism, functions, adverse effects along with various in vivo and in vitro models of evaluation of antioxidant activity of new molecule, compounds or any plant or plant part. This review is one of its kinds which will be of great importance for researchers working in this area in search of antioxidant moieties and their biological evaluation.
抗氧化剂是能够对抗动物组织中发生的氧化生理过程的破坏作用的物质。这些可能是营养物质（维生素和矿物质）以及我们体内协助化学反应的酶（蛋白质）。它们被认为在预防诸如癌症、糖尿病、心脏病、中风、阿尔茨海默病、类风湿性关节炎和白内障等慢性疾病的发展中发挥作用。本综述文章着重阐述了氧化剂和抗氧化剂的各个方面，即定义、类型、成因、机制、功能、不良影响，以及评估新分子、化合物或任何植物或植物部分抗氧化活性的各种体内和体外模型。这篇综述是同类综述中的一篇，对于在该领域寻找抗氧化部分及其生物学评估的研究人员具有重要意义。
