Jakubczyk Karolina, Kałduńska Justyna, Dec Karolina, Kawczuga Dorota, Janda Katarzyna
Department of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, Poland.
Institute of Biology, University of Szczecin, Poland.
Pol Merkur Lekarski. 2020 Apr 22;48(284):128-132.
Reactive oxygen species are molecules capable of independent existence, containing at least one oxygen atom and one or more unpaired electrons. Excessive formation of these molecules leads to oxidative stress. In recent years, there has been a growing interest in substances with antioxidant properties, reducing or preventing the harmful effects of free radicals. The compounds involved in antioxidant defence include endogenous and exogenous antioxidants, protecting body cells against the negative effects of oxygen radicals. The most important small-molecule non-enzymatic compounds found in food include ascorbic acid, retinol, β-carotene, tocopherol and polyphenolic compounds. Products of plant origin may provide a valuable source of bioactive compounds with antioxidant properties. It is believed that a diet rich in antioxidants may reduce the risk of developing several nutrition-related conditions as well as delay the ageing process. The aim of this review was to elucidate this topic and the state of the art about the role of plant orgin substances in counteraction of free radical reactions in human body.
活性氧是能够独立存在的分子，至少含有一个氧原子和一个或多个未成对电子。这些分子的过度形成会导致氧化应激。近年来，人们对具有抗氧化特性的物质越来越感兴趣，这些物质可以减少或预防自由基的有害影响。参与抗氧化防御的化合物包括内源性和外源性抗氧化剂，可保护人体细胞免受氧自由基的负面影响。食物中发现的最重要的小分子非酶化合物包括抗坏血酸、视黄醇、β-胡萝卜素、生育酚和多酚类化合物。植物源产品可能提供具有抗氧化特性的生物活性化合物的宝贵来源。据信，富含抗氧化剂的饮食可能会降低患几种营养相关疾病的风险，并延缓衰老过程。本综述的目的是阐明这一主题以及植物源物质在人体自由基反应对抗中的作用的最新研究状况。
