吊桥细胞照亮前额叶杏仁核输出的抑制性控制。
Chandelier Cells Illuminate Inhibitory Control of Prefrontal-Amygdala Outputs.
机构信息
Department of Psychology and Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA. Electronic address: https://twitter.com/TomGiustino.
Department of Psychology and Institute for Neuroscience, Texas A&M University, College Station, TX 77843, USA.
出版信息
Trends Neurosci. 2017 Nov;40(11):640-642. doi: 10.1016/j.tins.2017.09.005. Epub 2017 Oct 4.
Abstract
Inhibitory interneurons comprise a diverse subpopulation of cells that are critical to circuit function. How distinct inhibitory microcircuits control long-range projections remains poorly understood. A recent study by Lu and colleagues uncovered a unidirectional microcircuit of prefrontal chandelier cells that preferentially innervate and suppress long-range amygdala-projecting pyramidal cells.
摘要
抑制性中间神经元由多种细胞组成，对回路功能至关重要。不同的抑制性微回路如何控制长程投射仍知之甚少。最近，Lu 及其同事的一项研究揭示了前额叶篮状细胞的一个单向微回路，该微回路优先支配并抑制长程投射到杏仁核的锥体神经元。
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2
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Nature. 2016 Jul 21;535(7612):420-4. doi: 10.1038/nature18630. Epub 2016 Jul 13.
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