Sanidas Elias, Papadopoulos Dimitris P, Grassos Harris, Velliou Maria, Tsioufis Kostas, Barbetseas John, Papademetriou Vasilios
Department of Cardiology, Hypertension Excellence Centre-ESH, LAIKO General Hospital, Athens, Greece.
Department of Cardiology, Hypertension Excellence Centre-ESH, LAIKO General Hospital, Athens, Greece.
J Am Soc Hypertens. 2017 Nov;11(11):709-715. doi: 10.1016/j.jash.2017.09.008. Epub 2017 Sep 27.
Air pollution is one of the greatest environmental threats and has been implicated for several adverse cardiovascular effects including arterial hypertension (HTN). However, the exact relationship between air pollution exposure and HTN is still unclear. Air contamination provokes oxidative stress, systemic inflammation, and autonomic nervous system imbalance that subsequently induce endothelial dysfunction and vasoconstriction leading to increased blood pressure. The aim of this review was to describe the potential mechanisms by which air pollution contributes to HTN and to summarize the consequences of short- and long-term exposure.
空气污染是最大的环境威胁之一，与包括动脉高血压（HTN）在内的多种不良心血管效应有关。然而，空气污染暴露与HTN的确切关系仍不清楚。空气污染会引发氧化应激、全身炎症和自主神经系统失衡，进而导致内皮功能障碍和血管收缩，从而使血压升高。本综述的目的是描述空气污染导致HTN的潜在机制，并总结短期和长期暴露的后果。
