Delaviz Hamdollah, Mohammadi Jamshid, Ghalamfarsa Ghasem, Mohammadi Bahram, Farhadi Naser
Medicinal Plants Research Centre, Faculty of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran.
Department of Pediatrics, Yasuj University of Medical Sciences, Yasuj, Iran.
Pharmacogn Rev. 2017 Jul-Dec;11(22):145-152. doi: 10.4103/phrev.phrev_10_17.
In recent years, the use of medicinal plants increased considerably; so that today, the use of traditional medicine, as well as medicinal plants is necessary for the aim of producing more effective drugs with fewer side effects and determining the effective doses. With the scientific name of , walnut plant is a medicinal plant with different properties that is considered less, despite having great therapeutic potential in the traditional medicine. The aim of this study was to review the dispersal of walnut plants, the chemical compounds, and therapeutic effects of walnuts on antioxidant activity, antidiabetic, hypolipidemic, antimicrobial, and antihypertensive activities, as well as liver protection. Data of this review study have been collected from the books and scientific articles published in databases such as Science Direct, Web of Science, Scopus, PubMed, and Scientific Information Database. While this plant having high antioxidant capabilities, walnuts are composed of many chemical compounds such as ascorbic acid, flavonoids, quercetin, and caffeic acid. Experimental studies have shown that walnuts reduced blood glucose and lipids and also decreased blood pressure. They have antioxidant, antidiabetic, antimicrobial, and liver-protective properties. The use of walnuts in traditional medicine and review of experimental studies demonstrated the presence of multiple, effective, and useful compounds which may provide the opportunity for the production of lipid-lowering, antidiabetes, and liver protective drugs. Due to the effects of walnuts on improving the complications of various diseases, the need for doing comprehensive clinical trials for the use of walnuts in the treatment of diseases is necessary.
近年来,药用植物的使用量大幅增加;以至于如今,为了生产副作用更少的更有效药物并确定有效剂量,传统医学以及药用植物的使用变得十分必要。核桃植株的学名是 ,它是一种具有多种特性的药用植物,尽管在传统医学中具有巨大的治疗潜力,但人们对其的重视程度较低。本研究的目的是综述核桃植株的分布、化学成分以及核桃在抗氧化活性、抗糖尿病、降血脂、抗菌、抗高血压活性以及肝脏保护方面的治疗作用。本综述研究的数据收集自《科学Direct》《科学网》《Scopus》《PubMed》和《科学信息数据库》等数据库中发表的书籍和科学文章。虽然这种植物具有很高的抗氧化能力,但核桃由许多化学成分组成,如抗坏血酸、黄酮类化合物、槲皮素和咖啡酸。实验研究表明,核桃可降低血糖和血脂,还能降低血压。它们具有抗氧化、抗糖尿病、抗菌和肝脏保护特性。核桃在传统医学中的应用以及实验研究综述表明,其存在多种有效且有用的化合物,这可能为生产降脂、抗糖尿病和肝脏保护药物提供机会。由于核桃对改善各种疾病并发症的作用,有必要对核桃用于治疗疾病进行全面的临床试验。