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Immunotoxicology: A brief history, current status and strategies for future immunotoxicity assessment.

作者信息

Germolec Dori, Luebke Robert, Rooney Andrew, Shipkowski Kelly, Vandebriel Rob, van Loveren Henk

机构信息

Toxicology Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.

Cardiopulmonary and Immunotoxicology Branch, National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, NC.

出版信息

Curr Opin Toxicol. 2017 Aug;5:55-59. doi: 10.1016/j.cotox.2017.08.002.

DOI:10.1016/j.cotox.2017.08.002
PMID:28989989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5629009/
Abstract
摘要

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本文引用的文献

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Prediction of skin sensitization potency using machine learning approaches.使用机器学习方法预测皮肤致敏潜力。
J Appl Toxicol. 2017 Jul;37(7):792-805. doi: 10.1002/jat.3424. Epub 2017 Jan 10.
2
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice.从人类肠道中鉴定出单独就能在小鼠体内诱导肠道Th17细胞的共生细菌种类。
Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8141-E8150. doi: 10.1073/pnas.1617460113. Epub 2016 Nov 23.
3
Immune-Related Adverse Events Associated with Immune Checkpoint Inhibitors.与免疫检查点抑制剂相关的免疫相关不良事件。
BioDrugs. 2016 Dec;30(6):571-584. doi: 10.1007/s40259-016-0204-3.
4
Multivariate models for prediction of human skin sensitization hazard.预测人类皮肤致敏危害的多变量模型。
J Appl Toxicol. 2017 Mar;37(3):347-360. doi: 10.1002/jat.3366. Epub 2016 Aug 2.
5
Integrated decision strategies for skin sensitization hazard.皮肤致敏危害的综合决策策略
J Appl Toxicol. 2016 Sep;36(9):1150-62. doi: 10.1002/jat.3281. Epub 2016 Feb 6.
6
Adverse outcome pathways: From research to regulation scientific workshop report.不良结局途径：从研究到监管科学研讨会报告
Regul Toxicol Pharmacol. 2016 Apr;76:39-50. doi: 10.1016/j.yrtph.2016.01.007. Epub 2016 Jan 14.
7
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J Immunotoxicol. 2016;13(2):173-80. doi: 10.3109/1547691X.2015.1029147. Epub 2015 Mar 27.
8
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Integrated Testing Strategies (ITS) for safety assessment.集成测试策略 (ITS) 用于安全性评估。
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