Poli F, Claudel J-P, Auffret N, Leccia M-T, Dréno B
Cabinet privé, 2, rue Cherche-Midi, 75006 Paris, France.
Cabinet privé, 30, rue Michelet, 37000 Tours, France.
Ann Dermatol Venereol. 2017 Dec;144(12):768-775. doi: 10.1016/j.annder.2017.08.011. Epub 2017 Oct 6.
Acne is a chronic disease that may cause sequels such as atrophic or hypertrophic scars or post-inflammatory hyperpigmentation. Topical and systemic medications with proven pharmacologic activity and which have received marketing authorization are the key actors in the treatment of acne. However, these topical or systemic treatments frequently cause adverse effects related to impairment of the skin barrier, and cosmetics must therefore be used in combination to help protect the skin barrier. Nowadays, new cosmetic products containing active ingredients tested in vitro or in a small number of subjects have changed the world of cosmetics. In being described as "dermo-cosmetic" and in integrating active ingredients in their formulations, these cosmetics are now being presented as being specifically adapted for a given disease, and no longer limited to skin care and hygiene but suitable as an adjunctive or even an alternative to current medications. The aim of this article is to provide a better understanding of the respective roles of medications and cosmetics in the management of acne.
痤疮是一种慢性疾病，可能会导致诸如萎缩性或肥厚性瘢痕或炎症后色素沉着等后遗症。具有已证实的药理活性且已获得上市许可的局部和全身用药是痤疮治疗的关键因素。然而，这些局部或全身治疗常常会引起与皮肤屏障受损相关的不良反应，因此必须联合使用化妆品来帮助保护皮肤屏障。如今，含有在体外或少数受试者中进行过测试的活性成分的新型化妆品已改变了化妆品领域。这些化妆品被称为“皮肤化妆品”，并在其配方中加入了活性成分，现在它们被宣传为特别适用于特定疾病，不再局限于皮肤护理和卫生，而是适合作为当前药物的辅助手段甚至替代方法。本文旨在更深入地了解药物和化妆品在痤疮管理中的各自作用。
