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Spatial Gene Profiling in the Ischemic Heart: Fibroblasts Put on Their SOX.

作者信息

Khalil Hadi, Maillet Marjorie, Molkentin Jeffery D

机构信息

From Department of Pediatrics, University of Cincinnati (H.K., M.M., J.D.M.), and Howard Hughes Medical Institute (J.D.M.), Cincinnati Children's Hospital Medical Center, OH.

出版信息

Circulation. 2017 Oct 10;136(15):1410-1411. doi: 10.1161/CIRCULATIONAHA.117.030625.

DOI:10.1161/CIRCULATIONAHA.117.030625
PMID:28993372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5679745/
Abstract
摘要

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本文引用的文献

1
Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury.Tomo-Seq 鉴定 Sox9 为缺血性损伤中心脏纤维化的关键调节因子。
Circulation. 2017 Oct 10;136(15):1396-1409. doi: 10.1161/CIRCULATIONAHA.117.027832. Epub 2017 Jul 19.
2
Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture.类卵泡抑素-1促进心脏成纤维细胞活化并保护心脏免于破裂。
EMBO Mol Med. 2016 Aug 1;8(8):949-66. doi: 10.15252/emmm.201506151. Print 2016 Aug.
3
The fibrosis-cell death axis in heart failure.心力衰竭中的纤维化-细胞死亡轴
Heart Fail Rev. 2016 Mar;21(2):199-211. doi: 10.1007/s10741-016-9536-9.
4
Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration.空间分辨全基因组转录谱分析鉴定 BMP 信号作为斑马鱼心肌细胞再生的必要调节因子。
Dev Cell. 2016 Jan 11;36(1):36-49. doi: 10.1016/j.devcel.2015.12.010. Epub 2015 Dec 31.
5
The versatile functions of Sox9 in development, stem cells, and human diseases.Sox9在发育、干细胞及人类疾病中的多种功能。
Genes Dis. 2014 Dec;1(2):149-161. doi: 10.1016/j.gendis.2014.09.004.
6
Genome-wide RNA Tomography in the zebrafish embryo.斑马鱼胚胎的全基因组 RNA 断层扫描技术
Cell. 2014 Oct 23;159(3):662-75. doi: 10.1016/j.cell.2014.09.038.
7
SOX9 Is Highly Expressed in Nonampullary Duodenal Adenoma and Adenocarcinoma in Humans.SOX9 在人类非壶腹十二指肠腺瘤和腺癌中高度表达。
Gut Liver. 2013 Sep;7(5):513-8. doi: 10.5009/gnl.2013.7.5.513. Epub 2013 Jun 11.
8
Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development.在小鼠心脏瓣膜发育过程中，Sox9是前体细胞扩张和细胞外基质组织所必需的。
Dev Biol. 2007 May 1;305(1):120-32. doi: 10.1016/j.ydbio.2007.02.002. Epub 2007 Feb 7.
9
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa.Sox9在控制心脏瓣膜和间隔形成的途径中起关键作用。
Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6502-7. doi: 10.1073/pnas.0401711101. Epub 2004 Apr 19.
10
SOX9 directly regulates the type-II collagen gene.SOX9直接调控II型胶原蛋白基因。
Nat Genet. 1997 Jun;16(2):174-8. doi: 10.1038/ng0697-174.