台湾成人T细胞白血病/淋巴瘤患者中HTLV-I前病毒DNA的存在情况。
Presence of HTLV-I proviral DNA in patients with adult T-cell leukemia/lymphoma in Taiwan.
作者信息
Kuo T T, Sato H, Dunn P, Shih L Y, Eimoto T, Kikuchi M, Maeda Y
机构信息
Department of Pathology, Chang Gung Medical College, Taipei, Taiwan, Republic of China.
出版信息
Cancer. 1988 Aug 15;62(4):702-4. doi: 10.1002/1097-0142(19880815)62:4<702::aid-cncr2820620409>3.0.co;2-i.
Abstract
Human T-lymphotropic virus-I (HTLV-I) proviral DNA was demonstrated in the leukemic cells of two newly identified cases of adult T-cell leukemia/lymphoma (ATL) in Taiwan by the Southern blot hybridization method. Therefore, the ATL cases diagnosed clinicopathologically in Taiwan were, for the first time, documented to be definitely related to HTLV-I.
摘要
通过Southern印迹杂交法，在台湾新确诊的两例成人T细胞白血病/淋巴瘤（ATL）患者的白血病细胞中检测到了人类嗜T淋巴细胞病毒I型（HTLV-I）前病毒DNA。因此，台湾地区经临床病理诊断的ATL病例首次被证实与HTLV-I明确相关。
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