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L-myc 限制性片段长度多态性与人类结直肠癌恶性程度之间无相关性。

No correlation between L-myc restriction fragment length polymorphism and malignancy of human colorectal cancers.

作者信息

Ikeda I, Ishizaka Y, Ochiai M, Sakai R, Itabashi M, Onda M, Sugimura T, Nagao M

机构信息

Carcinogenesis Division, National Cancer Center Research Institute, Tokyo.

出版信息

Jpn J Cancer Res. 1988 Jun;79(6):674-6. doi: 10.1111/j.1349-7006.1988.tb02220.x.

DOI:10.1111/j.1349-7006.1988.tb02220.x
PMID:2900827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5917581/
Abstract

The correlation of the restriction fragment length polymorphism (RFLP) pattern of L-myc with the progressive state of cancer and metastases to lymph nodes or other organs were examined in 35 cases of human colorectal cancer by chi 2 analysis. No significant correlation was found.

摘要

通过卡方分析，对35例人类结直肠癌患者的L-myc限制片段长度多态性（RFLP）模式与癌症进展状态以及淋巴结或其他器官转移之间的相关性进行了研究。未发现显著相关性。

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No correlation between L-myc restriction fragment length polymorphism and malignancy of human colorectal cancers.L-myc 限制性片段长度多态性与人类结直肠癌恶性程度之间无相关性。
Jpn J Cancer Res. 1988 Jun;79(6):674-6. doi: 10.1111/j.1349-7006.1988.tb02220.x.
2
Close correlation between restriction fragment length polymorphism of the L-MYC gene and metastasis of human lung cancer to the lymph nodes and other organs.L-MYC基因的限制性片段长度多态性与人肺癌向淋巴结及其他器官转移之间的密切相关性。
Proc Natl Acad Sci U S A. 1988 Apr;85(7):2353-6. doi: 10.1073/pnas.85.7.2353.
3
Ha-ras-1 restriction fragment length polymorphism and susceptibility to colon adenocarcinoma.Ha-ras-1限制性片段长度多态性与结肠腺癌易感性
Br J Cancer. 1987 Jul;56(1):1-5. doi: 10.1038/bjc.1987.143.
4
[Loss of heterozygosity involving DCC gene in human colorectal cancers is correlated with the metastatic potential].
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Expression of the c-myc gene in human gastrointestinal malignancies.c-myc基因在人类胃肠道恶性肿瘤中的表达。
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Clonal analysis of human colorectal tumors.人类结肠肿瘤的克隆分析。
Science. 1987 Oct 9;238(4824):193-7. doi: 10.1126/science.2889267.
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Correlation of L-myc RFLP with metastasis, prognosis and multiple cancer in lung-cancer patients.肺癌患者中L-myc限制性片段长度多态性与转移、预后及多种癌症的相关性。
Int J Cancer. 1992 Feb 20;50(4):557-61. doi: 10.1002/ijc.2910500411.

引用本文的文献

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L-myc restriction fragment length polymorphism in Japanese patients with esophageal cancer.日本食管癌患者的L-myc限制性片段长度多态性
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MYCL genotypes and loss of heterozygosity in non-small-cell lung cancer.非小细胞肺癌中的MYCL基因型与杂合性缺失
Br J Cancer. 1996 Dec;74(12):1975-8. doi: 10.1038/bjc.1996.662.
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Simultaneous detection of genetic and immunological markers in non-small cell lung cancer: prediction of metastatic potential of tumor.非小细胞肺癌中基因和免疫标志物的同步检测：肿瘤转移潜能的预测
Clin Exp Metastasis. 1996 Nov;14(6):490-500. doi: 10.1007/BF00115109.
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Coamplification of the L-myc and N-myc oncogenes in a neuroblastoma cell line.神经母细胞瘤细胞系中L-myc和N-myc癌基因的共扩增。
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Br J Cancer. 1990 Jun;61(6):809-12. doi: 10.1038/bjc.1990.182.
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Restriction fragment length polymorphism of the L-myc gene in oral cancer patients.口腔癌患者中L-myc基因的限制性片段长度多态性
Br J Cancer. 1990 Apr;61(4):530-3. doi: 10.1038/bjc.1990.119.
7
Proto-oncogene allelic variations in human squamous cell carcinomas of the larynx.
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8
Relationship of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis.H-ras-1、L-myc和p53基因多态性与肺癌风险及预后的关系
Environ Health Perspect. 1992 Nov;98:61-7. doi: 10.1289/ehp.929861.

本文引用的文献

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Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage.未经治疗的人类神经母细胞瘤中N - myc的扩增与疾病晚期相关。
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Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.由于DNA扩增导致人类基因N-myc表达增强，可能促使神经母细胞瘤发生恶性进展。
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L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer.L-myc，一种在人类小细胞肺癌中扩增并表达的新的与myc相关的基因。
Nature. 1985;318(6041):69-73. doi: 10.1038/318069a0.