MYC5 参与茉莉酸调控的植物生长、叶片衰老和防御反应。

MYC5 is Involved in Jasmonate-Regulated Plant Growth, Leaf Senescence and Defense Responses.

机构信息

Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, College of Life Sciences, Capital Normal University, Beijing 100048, China.

Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.

出版信息

Plant Cell Physiol. 2017 Oct 1;58(10):1752-1763. doi: 10.1093/pcp/pcx112.

DOI:10.1093/pcp/pcx112

PMID:29017003

Abstract

Jasmonates (JAs), lipid-derived phytohormones, regulate plant growth, development and defenses against biotic stresses. CORONATINE INSENSITIVE1 perceives bioactive JA and recruits JASMONATE ZIM-DOMAIN (JAZ) proteins for ubiquitination and subsequent degradation via the 26S proteasome, which de-represses JAZ-targeted transcription factors that regulate diverse JA responses. Recent studies showed that the Arabidopsis basic helix-loop-helix transcription factor MYC5 interacts with JAZs and regulates stamen development. However, whether MYC5 mediates other JA responses is unclear. Here, we show that MYC5 functions redundantly with MYC2, MYC3 and MYC4 to modulate JA-regulated root growth inhibition and plant defenses against insect attack and pathogen infection, and that it positively regulates JA-induced leaf senescence. Our findings define MYC5 as an important regulator that is essential for diverse JA responses.

摘要

茉莉酸（JAs），脂衍生的植物激素，调节植物的生长、发育和对生物胁迫的防御。茉莉酸不敏感 1 感知生物活性 JA 并招募茉莉酸 ZIM 结构域（JAZ）蛋白进行泛素化和随后通过 26S 蛋白酶体降解，这解除了 JAZ 靶向转录因子对调节各种 JA 反应的抑制。最近的研究表明，拟南芥基本螺旋-环-螺旋转录因子 MYC5 与 JAZs 相互作用并调节雄蕊发育。然而，MYC5 是否介导其他 JA 反应尚不清楚。在这里，我们表明 MYC5 与 MYC2、MYC3 和 MYC4 冗余地发挥作用，以调节 JA 调节的根生长抑制和植物对昆虫攻击和病原体感染的防御，并且它正向调节 JA 诱导的叶片衰老。我们的研究结果定义了 MYC5 作为一个重要的调节剂，对于各种 JA 反应是必不可少的。