食物过敏儿童肠道微生物群失调的初步研究。

A preliminary study of gut dysbiosis in children with food allergy.

作者信息

Inoue Ryo, Sawai Toshihiro, Sawai Chihiro, Nakatani Masako, Romero-Pérez Gustavo A, Ozeki Motoyuki, Nonomura Kazuo, Tsukahara Takamitsu

机构信息

a Laboratory of Animal Science, Department of Agricultural and Life Sciences , Kyoto Prefectural University , Kyoto , Japan.

b Department of Pediatrics , Shiga University of Medical Science , Shiga , Japan.

出版信息

Biosci Biotechnol Biochem. 2017 Dec;81(12):2396-2399. doi: 10.1080/09168451.2017.1383849. Epub 2017 Oct 11.

DOI:10.1080/09168451.2017.1383849

PMID:29017394

Abstract

Gut microbiota of food allergic children was analyzed by high throughput 16S rRNA gene sequencing. Signs of gut dysbiosis, which is likely associated with gut inflammation, was observed in children with food allergies. For example, decreased abundance of genus Akkermansia but increased abundance of Veillonella was found in children with food allergy in comparison with healthy control children.

摘要

通过高通量16S rRNA基因测序分析了食物过敏儿童的肠道微生物群。在食物过敏儿童中观察到肠道生态失调的迹象，这可能与肠道炎症有关。例如，与健康对照儿童相比，食物过敏儿童中阿克曼氏菌属丰度降低，但韦荣氏菌属丰度增加。