Providência Joana, Ponces Filipa, Castela Guilherme, Murta Joaquim
Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra EPE, Coimbra, Coimbra, Portugal.
Faculdade de Medicina, University of Coimbra.
BMJ Case Rep. 2017 Oct 10;2017:bcr-2017-221624. doi: 10.1136/bcr-2017-221624.
A 42-year-old woman presented with chronic history of left red eye for more than 12 months, treated with difference topical medication but without response. Ocular external examination demonstrated a firm palpable mass in the medial portion of the lower eyelid and slit-lamp evaluation of the lesion showed an ulcerated conjunctival nodule, keratin secretor. CT of the orbits revealed left-sided orbital mass located anteriorly, inferiorly and medially in the orbit, adjacent to the globe and orbit walls. Incisional biopsy of the lesion was consistent with invasive squamous cell carcinoma of the conjunctiva. As the tumour had no response to initial adjuvant systemic chemotherapy, exenteration of left orbit was performed due to advanced disease.
一名42岁女性,左眼红眼病史长达12个月以上,曾使用多种局部药物治疗但无效果。眼部外部检查显示下眼睑内侧可触及一个质地坚硬的肿块,裂隙灯检查该病变显示为一个溃疡的结膜结节,有角质分泌。眼眶CT显示左侧眼眶肿块位于眼眶前部、下部和内侧,毗邻眼球和眼眶壁。病变的切开活检结果符合结膜浸润性鳞状细胞癌。由于肿瘤对初始辅助全身化疗无反应,因病情进展行左侧眼眶内容剜除术。