Lee L R, Sullivan T J, Vandeleur K
Department of Ophthalmology, Royal Brisbane Hospital, Queensland, Australia.
Aust N Z J Ophthalmol. 1997 Feb;25(1):75-7. doi: 10.1111/j.1442-9071.1997.tb01280.x.
Orbital squamous cell carcinoma following retinal detachment surgery is a rare condition. A proposed pathogenesis involves implantation of conjunctival squamous epithelium at the time of surgery, with subsequent malignant transformation.
METHODS/RESULTS: An 81-year-old Caucasian man presented with a six-month history of a discharging painful red right eye. Ten years earlier a right scleral buckling with an encircling sponge exoplant had been performed. Examination revealed exposure of the sponge, and a large mass in the superomedial conjunctival fornix. Computed tomography revealed a mass invading around the globe in the region of the exoplant. Biopsy revealed squamous cell carcinoma. Orbital exenteration was performed.
Orbital squamous cell carcinoma may arise following retinal detachment surgery presumably due to iatrogenic conjunctival implantation deep in the orbit.
视网膜脱离手术后发生眼眶鳞状细胞癌是一种罕见情况。一种推测的发病机制涉及手术时结膜鳞状上皮的植入，随后发生恶性转化。
方法/结果：一名81岁的白种男性，右眼疼痛、发红且有分泌物，病程6个月。10年前曾行右眼巩膜扣带术并植入环形海绵外植体。检查发现海绵外露，结膜上穹隆部有一巨大肿物。计算机断层扫描显示肿物侵犯外植体周围的眼球。活检显示为鳞状细胞癌。遂行眼眶内容物剜除术。
眼眶鳞状细胞癌可能在视网膜脱离手术后发生，推测是由于医源性结膜植入至眼眶深部所致。
