Parkes Rebekah J, Parkes Gary, James Kyle
School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Department of Surgery, United Mission Hospital Tansen, Tansen, Nepal.
BMJ Glob Health. 2017 Sep 25;2(3):e000313. doi: 10.1136/bmjgh-2017-000313. eCollection 2017.
Femoral shaft fractures carry considerable morbidity and are increasingly common in less economically developed countries (LEDCs). Treatment options include traction and intramedullary (IM) nailing but in a limited-resource environment; cost-effectiveness is fundamental to policy development. The objective herein was to evaluate the cost-effectiveness of moving from traction to IM nailing for femoral shaft fractures, in adults, in LEDCs. Incorporating a systematic review of complications and functional outcomes and a cost-minimization analysis.
PubMed, EMBASE, Africa Journals Online and the Cochrane Library were searched from inception using the terms: femur* AND fracture AND traction AND (sign OR nail* OR intramedullary) AND (cost-effectiveness OR cost* OR outcome OR function) NOT paed* NOT child* NOT elastic NOT neck NOT intertrochanteric NOT periprosthetic (where asterisks indicate an unlimited truncation strategy). Abstracts were reviewed for all titles returned and full texts obtained as indicated. References of all relevant papers were also examined for further studies.
IM nailing has been successfully used in several institutions and reported infection, union and reoperation rates are encouraging, although no randomised control trials were identified. Three studies assessed the cost aspect and all found IM nailing to be the cheaper strategy.
To date, the improved complication profile and reduced cost of treatment suggest that IM nailing is more cost-effective than traction. Evidence, however, is limited and the necessity for appropriate training and audit with the introduction of new techniques must be emphasised.
股骨干骨折会导致相当高的发病率,且在经济欠发达国家(LEDCs)越来越常见。治疗选择包括牵引和髓内(IM)钉固定,但在资源有限的环境中,成本效益对于政策制定至关重要。本文的目的是评估在LEDCs的成年人中,将股骨干骨折的治疗从牵引改为IM钉固定的成本效益。纳入对并发症和功能结果的系统评价以及成本最小化分析。
从创刊号开始检索PubMed、EMBASE、非洲在线期刊和Cochrane图书馆,使用的检索词为:股骨* AND 骨折 AND 牵引 AND (体征 OR 钉* OR 髓内) AND (成本效益 OR 成本* OR 结果 OR 功能) NOT 儿科* NOT 儿童* NOT 弹性 NOT 颈部 NOT 转子间 NOT 假体周围(星号表示无限截断策略)。对所有返回标题的摘要进行了审查,并按指示获取了全文。还检查了所有相关论文的参考文献以寻找进一步的研究。
IM钉固定已在多个机构成功使用,报告的感染、愈合和再次手术率令人鼓舞,尽管未找到随机对照试验。三项研究评估了成本方面,均发现IM钉固定是成本更低的策略。
迄今为止,并发症情况的改善和治疗成本的降低表明,IM钉固定比牵引更具成本效益。然而,证据有限,必须强调引入新技术时进行适当培训和审计的必要性。