饮食如何影响肠道微生物群以促进或危害健康。
How diet can impact gut microbiota to promote or endanger health.
作者信息
Chassaing Benoit, Vijay-Kumar Matam, Gewirtz Andrew T
机构信息
aNeuroscience Institute bInstitute for Biomedical Sciences, Georgia State University, Atlanta,Georgia cDepartment of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA.
出版信息
Curr Opin Gastroenterol. 2017 Nov;33(6):417-421. doi: 10.1097/MOG.0000000000000401.
PURPOSE OF REVIEW
Disturbances of the intestinal microbiota have been increasingly implicated in driving various diseases associated with a broad range of chronic inflammatory state. Such diseases have increased in incidence since the mid-20th century, and have roughly correlated with societal changes in food production during this period.
RECENT FINDINGS
Considering how changes in diet may have impacted gut microbiota and exploring whether targeted modulations of diet might be a means of optimizing microbiota composition to promote health.
SUMMARY
Recent literature demonstrates that modulation of diet has potential to both beneficially and detrimentally impact microbiota composition and how it interacts with its host. Herein, we discuss recent studies by ourselves and others that demonstrate the potential for changes in diet to have profound impacts on the gut microbiota in ways that can have beneficial or detrimental effects on host health.
综述目的
肠道微生物群紊乱越来越多地被认为是引发各种与广泛慢性炎症状态相关疾病的原因。自20世纪中叶以来，这类疾病的发病率不断上升，并且大致与这一时期食品生产的社会变化相关。
最新发现
考虑饮食变化如何影响肠道微生物群，并探索有针对性的饮食调节是否可能是优化微生物群组成以促进健康的一种手段。
总结
最近的文献表明，饮食调节有可能对微生物群组成及其与宿主的相互作用产生有益或有害的影响。在此，我们讨论我们自己和其他人最近的研究，这些研究表明饮食变化有可能以对宿主健康产生有益或有害影响的方式对肠道微生物群产生深远影响。
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